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  1. Article

    Open Access

    Investigation of pathogenesis of hyperuricemia based on untargeted and targeted metabolomics

    Hyperuricemia (HUA) seriously harms human health but the exact etiology and pathogenesis of HUA are not fully understood. Therefore, it is still of great significance to find effective biomarkers and explore t...

    Nankun Qin, Ming Qin, Wenjun Shi, Lingbo Kong, Liting Wang, Guang Xu in Scientific Reports (2022)

  2. Article

    Open Access

    Lipidomics study of the therapeutic mechanism of Plantaginis Semen in potassium oxonate-induced hyperuricemia rat

    Plantaginis Semen has been widely used as folk medicine and health care food against hyperuricemia (HUA) and gout, but its pharmacological mechanism remains unclear. This study investigated the therapeutic mec...

    Fei Yang, Wenjun Shi, Liting Wang, Nankun Qin in BMC Complementary Medicine and Therapies (2021)

  3. Article

    Open Access

    Lipidomics coupled with pathway analysis characterizes serum metabolic changes in response to potassium oxonate induced hyperuricemic rats

    Hyperuricemia as a metabolic disease is usually associated with lipid metabolic disorder. The purpose of this study is to identify potential lipid biomarkers and provide the evidence for the relationship betwe...

    Fei Yang, Mingyu Liu, Nankun Qin, Shuangshuang Li in Lipids in Health and Disease (2019)