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  1. Article

    Open Access

    Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms

    The endocannabinoid (eCB) system and the serotonin (5-HT) are both implicated in the severity of the depression. 5-HT is synthesized from the amino acid tryptophan (Trp), which is also a precursor for kynureni...

    Stefano Comai, Nicolas Nunez, Tobias Atkin, Maykel F. Ghabrash in BMC Medicine (2024)

  2. No Access

    Article

    Preeclampsia and the longitudinal risk of hospitalization for depression at 28 years

    The association between pregnancy characteristics and risk of depression in women is poorly understood. We investigated the relationship between preeclampsia and risk of hospitalization for depression over thr...

    Nathalie Auger, Nancy Low, Gilles Paradis in Social Psychiatry and Psychiatric Epidemio… (2021)

  3. Article

    Open Access

    Cannabis use disorder and the future risk of cardiovascular disease in parous women: a longitudinal cohort study

    Cannabis use is increasing in women of reproductive age, but whether cannabis use disorders increase the long-term risk of cardiovascular disease in this population is not known. Cannabis may cause tachycardia...

    Nathalie Auger, Gilles Paradis, Nancy Low, Aimina Ayoub, Siyi He in BMC Medicine (2020)

  4. No Access

    Article

    Risk of central nervous system defects in offspring of women with and without mental illness

    We sought to determine the relationship between maternal mental illness and the risk of having an infant with a central nervous system defect. We analyzed a cohort of 654,882 women aged less than 20 years betw...

    Aimina Ayoub, William D Fraser, Nancy Low in Archives of Women's Mental Health (2018)

  5. Article

    Open Access

    Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study

    Some authors have hypothesized that Treatment-Resistant Unipolar Depression (TRD-UP) should be considered within the bipolar spectrum disorders and that hidden bipolarity may be a risk factor for TRD-UP. Howev...

    Nicolas A. Nuñez, Stefano Comai, Eduard Dumitrescu, Maykel F. Ghabrash in BMC Psychiatry (2018)