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Article
Open AccessIdentification of sulfakinin receptor regulating feeding behavior and hemolymph trehalose homeostasis in the silkworm, Bombyx mori
Feeding behavior, the most fundamental physiological activity, is controlled by two opposing groups of factors, orexigenic and anorexigenic factors. The sulfakinin family, an insect analogue of the mammalian s...
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Article
Open AccessMulti-omics analysis uncovered systemic lupus erythematosus and COVID-19 crosstalk
Studies have highlighted a possible crosstalk between the pathogeneses of COVID-19 and systemic lupus erythematosus (SLE); however, the interactive mechanisms remain unclear. We aimed to elucidate the impact o...
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Article
Open AccessHigh-affinity monoclonal antibodies against the porcine epidemic diarrhea virus S1 protein
The porcine epidemic diarrhea virus (PEDV) infection inflicted substantial economic losses upon the global pig-breeding industry. This pathogen can infect all pigs and poses a particularly high fatality risk f...
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Article
Open AccessTranscriptomic effects of paternal cocaine-seeking on the reward circuitry of male offspring
It has been previously established that paternal development of a strong incentive motivation for cocaine can predispose offspring to develop high cocaine-seeking behavior, as opposed to sole exposure to the d...
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Article
Open AccessPaternal cocaine-seeking motivation defines offspring’s vulnerability to addiction by down-regulating GABAergic GABRG3 in the ventral tegmental area
Epidemiological investigations indicate that parental drug abuse experiences significantly influenced the addiction vulnerability of offspring. Studies using animal models have shown that paternal cocaine use ...
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Diamond-Graphene Nanohybrid (DGN) Films: Preparation, Characterization and Application
) films combine the advantages hybridized carbon. They possess the features of , superior electricity, high transparency, . This chapter in detail has summarized the strategies to prepare the DGN fil...
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Open AccessSNORA56-mediated pseudouridylation of 28 S rRNA inhibits ferroptosis and promotes colorectal cancer proliferation by enhancing GCLC translation
Colorectal cancer (CRC) is one of the most common malignancies and is characterized by reprogrammed metabolism. Ferroptosis, a programmed cell death dependent on iron, has emerged as a promising strategy for C...
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Identifying the Interaction Between Tuberculosis and SARS-CoV-2 Infections via Bioinformatics Analysis and Machine Learning
The number of patients with COVID-19 caused by severe acute respiratory syndrome coronavirus 2 is still increasing. In the case of COVID-19 and tuberculosis (TB), the presence of one disease affects the infect...
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Open AccessEndoscopic surgery versus intensity-modulated radiotherapy in locally advanced recurrent nasopharyngeal carcinoma: a multicenter, case-matched comparison
The management of locally advanced recurrent nasopharyngeal carcinoma (rNPC) is challenging. The objective of our study was to compare salvage endoscopic nasopharyngectomy (ENPG) with intensity-modulated radio...
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Open AccessExploring the diagnostic and prognostic value of the C-reactive protein/lymphocyte ratio for dilated cardiomyopathy based on a real-world study
To determine the risk factors for dilated cardiomyopathy (DCM) and construct a risk model for predicting HF in patients with DCM, We enrolled a total of 2122 patients, excluding those who did not meet the requ...
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Article
SNORD11B-mediated 2′-O-methylation of primary let-7a in colorectal carcinogenesis
Evidence indicates that small nucleolar RNAs (snoRNAs) participate in tumorigenesis and development and could be promising biomarkers for colorectal cancer (CRC). Here, we examine the profile of snoRNAs in CRC...
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Open AccessCharacterization of monoclonal antibodies against porcine epidemic diarrhea virus S1/S2 junction protein
Pig producers have faced considerable economic losses due to porcine epidemic diarrhea virus (PEDV) infection, emphasizing the need for PEDV antibody development. The S1/S2 junction (S1S2J) cleavage site of th...
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Article
Fuzzy Approximation-Based Backstep** Control of Permanent Magnet Synchronous Motor
A permanent magnet synchronous motor(PMSM) control system based on backstep** control can effectively improve the dynamic performance, and the design process is simple and easy to be implemented in engineeri...
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Article
Open AccessThrowing and manipulating and cheating with a DNA nano-dice
Artificial molecular machines have captured the imagination of researchers, given their clear potential to mimic and influence human life. Key to behavior simulation is to reproduce the specific properties of ...
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Article
Open AccessAdoptive cellular immunotherapy for solid neoplasms beyond CAR-T
In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T) therapy are two milestone achievements in clinical immunotherapy. However, both show limited efficacies in most solid ...
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Article
Microstructure and mechanical properties of Cr films deposited with different peak powers by high-power impulse magnetron sputtering
For high-power impulse magnetron sputtering (HIPIMS), the peak power applied to the target is of great importance for regulating the ionization degree of the metal target and ion/atom flux ratio. In this work,...
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Article
[68Ga]Ga-FAPI PET/CT Improves the T Staging of Patients with Newly Diagnosed Nasopharyngeal Carcinoma: A Comparison with [18F]F-FDG
This study aimed to explore the value of [68Ga]Ga-labelled fibroblast activation protein inhibitor ([68Ga]Ga-FAPI) positron emission tomography/computed tomography (PET/CT) in the initial staging of patients with...
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Article
Natural Vegetation Encroachment Improves Nutritional Conditions of Bauxite Residue Disposal Area
The deficiencies of certain nutrients limit plant growth in bauxite residue disposal areas. In this study, residue samples at different depths (0–2 cm, 2–10 cm, 10–20 cm, 20–40 cm, and 40–60 cm) and stacking a...
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Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells
Transferrin receptor 1 (TfR1), encoded by TFRC, is a key regulator of iron homeostasis and plays important roles in many diseases, including cancers.
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Open AccessDiffusion kurtosis imaging and dynamic contrast-enhanced MRI for the differentiation of parotid gland tumors
To assess the usefulness of combined diffusion kurtosis imaging (DKI) and dynamic contrast-enhanced MRI (DCE-MRI) in the differentiation of parotid gland tumors.
