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Article
Synthesis of substituted cinnamoyl-tyramine derivatives and their platelet anti-aggregatory activities
Substituted cinnamoyl-tyramine derivatives were synthesized by DCC-coupling of substituted cinnamic acid with tyramine or tyramine methyl-1-ether to evaluate PAF-receptor binding antagonistic activities and in...
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Article
The facile and efficient synthesis of 8-chloroadenosine 3′,5′-cyclic monophosphate by phosphorylative cyclization of 8-chloroadenosine and its characterization by1H and13C NMR spectroscopy
Purine nucleosides were chlorinated by the reaction of acyl chloride in DMF with MCPBA under mild conditions with moderate yields. And, satisfactory method for the synthesis of ribonucleoside-3′,5′-cyclic phos...
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Article
Comparative study of extraction techniques for determination of garlic flavor components by gas chromatography–mass spectrometry
Several sampling techniques based on steam distillation (SD), simultaneous distillation and solvent extraction (SDE), solid-phase trap** solvent extraction (SPTE), and headspace solid-phase microextraction (...
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Article
Pharmacokinetics and tissue distribution of a novel PDE5 inhibitor, SK-3530, in rats
To investigate the pharmacokinetic profile and tissue distribution of a novel phosphodiesterase type 5 inhibitor, 5-ethyl-2-{5-[4-(2-hydroxy-ethyl)-piperazine-1-sulfonyl]-2-propoxy-phenyl}-7-propyl-3,5-dihydro...
