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    Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells

    Toll-like receptors (TLRs) recognize distinct microbial components and induce innate immune responses. TLR5 is triggered by bacterial flagellin. Here we generated Tlr5−/− 1mice and assessed TLR5 function in vivo....

    Satoshi Uematsu, Myoung Ho Jang, Nicolas Chevrier, Zi** Guo… in Nature Immunology (2006)