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Article
Open AccessEvolocumab-Based LDL-C Management in High and Very High Cardiovascular Risk Patients in German Clinical Practice: The HEYMANS Study
Low-density lipoprotein cholesterol (LDL-C) is among the most important modifiable risk factors for cardiovascular disease. In very high-risk patients, the European Society of Cardiology/European Atheroscleros...
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Article
Open AccessEvolocumab effectiveness in the real-world setting: Austrian data from the pan-European observational HEYMANS study
This real-world study examined clinical characteristics and dyslipidemia management among patients initiating evolocumab across 12 European countries. Austrian data are reported.
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Article
Open AccessPhysical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study
Multimorbidity is an emerging public health priority. Physical activity (PA) is recommended as one of the main lifestyle behaviours, yet the benefits of PA for people with multimorbidity are unclear. We assess...
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Article
Open AccessGlobal burden of hypoglycaemia-related mortality in 109 countries, from 2000 to 2014: an analysis of death certificates
In the context of increasing prevalence of diabetes in elderly people with multimorbidity, intensive glucose control may increase the risk of severe hypoglycaemia, potentially leading to death. While rising tr...
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Article
Open AccessPredicting hospital stay, mortality and readmission in people admitted for hypoglycaemia: prognostic models derivation and validation
Hospital admissions for hypoglycaemia represent a significant burden on individuals with diabetes and have a substantial economic impact on healthcare systems. To date, no prognostic models have been developed...
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Article
Open AccessNonlinear association of BMI with all-cause and cardiovascular mortality in type 2 diabetes mellitus: a systematic review and meta-analysis of 414,587 participants in prospective studies
The relationship between BMI and mortality has been extensively investigated in the general population; however, it is less clear in people with type 2 diabetes. We aimed to assess the association of BMI with ...
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Article
Open AccessLong terms trends of multimorbidity and association with physical activity in older English population
Multimorbidity has become one of the main challenges in the recent years for patients, health care providers and the health care systems globally. However, literature describing the burden of multimorbidity in...
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Article
Open AccessSmoking cessation advice recorded during pregnancy in United Kingdom primary care
United Kingdom (UK) national guidelines recommend that all pregnant women who smoke should be advised to quit at every available opportunity, and brief cessation advice is an efficient and cost-effective means...
