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Prevention of graft-versus-host-disease with preserved graft-versus-leukemia-effect by ex vivo and in vivo modulation of CD4+ T-cells

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  1. Article

    Open Access

    Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality

    Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies. Therefore, the key factor for cell viab...

    Nadine von Auw, Robert Serfling, Reni Kitte, Nadja Hilger… in Scientific Reports (2023)

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  2. Article

    Open Access

    Disruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation

    Transcription factor C/EBPα is a master regulator of myelopoiesis and its inactivation is associated with acute myeloid leukemia. Deregulation of C/EBPα by microRNAs during granulopoiesis or acute myeloid leuk...

    Alexander Arthur Wurm, Polina Zjablovskaja, Miroslava Kardosova… in Nature Communications (2017)

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