2 Result(s)
within
Nadja Hilger
Science, Humanities and Social Sciences, multidisciplinary
Science, multidisciplinary
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Article
Open AccessComparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality
Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies. Therefore, the key factor for cell viab...
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Article
Open AccessDisruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation
Transcription factor C/EBPα is a master regulator of myelopoiesis and its inactivation is associated with acute myeloid leukemia. Deregulation of C/EBPα by microRNAs during granulopoiesis or acute myeloid leuk...
