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  1. No Access

    Article

    Development of a small Beta-NMR system using Halbach Array permanent magnet

    We have developed a new and compact β-nuclear magnetic resonance (NMR) system using beta-radioactive nuclei. By using a Halbach array permanent magnet to create a static magnetic field, and a scintillating fib...

    Y. Kimura, M. Mihara, K. Matsuta, M. Fukuda, Y. Otani… in Hyperfine Interactions (2021)

  2. No Access

    Article

    Application of spin polarized 19O beam to the study of oxygen motion in solid oxide fuel cell materials

    The spin-lattice relaxation times T1 of an unstable nucleus 19O (T1/2 = 26.9 s, I = 5/2) implanted into Y2O3 stabilized ZrO2 (YSZ), which is a solid oxide fuel cell material, were measured at T = 278 − 333 K by m...

    Y. Otani, M. Mihara, K. Matsuta, M. Fukuda, R. Wakabayashi… in Hyperfine Interactions (2021)

  3. Article

    Open Access

    Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1

    24(S)-hydroxycholesterol (24S-OHC), which is enzymatically produced in the brain, has an important role in maintaining brain cholesterol homeostasis. We have previously reported that 24S-OHC induces necroptosi...

    K Yamanaka, Y Urano, W Takabe, Y Saito, N Noguchi in Cell Death & Disease (2014)

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  4. Article

    Oxidative stress induces insulin resistance by activating the nuclear factor-κB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

    Oxidative stress is associated with diabetes, hypertension and atherosclerosis. Insulin resistance is implicated in the development of these disorders. We tested the hypothesis that oxidative stress induces in...

    T. Ogihara, T. Asano, H. Katagiri, H. Sakoda, M. Anai, N. Shojima, H. Ono… in Diabetologia (2004)

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  5. No Access

    Article

    Effects of a new angiotensin-converting enzyme inhibitor, alacepril, on changes in neurohormonal factors and arterial baroreflex sensitivity in patients with congestive heart failure

    Objective: Patients with heart failure have abnormal neurohormonal regulation during orthostatic stress, and abnormal arterial baroreflex function. This study investigated the effects of...

    T. Kinugawa, M. Kato, M. Mori, A. Endo… in European Journal of Clinical Pharmacology (1998)

  6. No Access

    Chapter

    One-Electron Photooxidation Of Nadh: Laser Photolysis, Time-Resolved Raman And Ab Initio Mo Calculation Study

    Although the enzymatically mediated oxidation of NADH (reduced form of nicotinamide adenine dinucleotide) into NAD+ (oxidized form) is generally believed to proceed in a single step by a hydride ion (H−) transfer...

    N. Noguchi, M. Tachikawa, H. Takahashi in Spectroscopy of Biological Molecules: Mode… (1997)

  7. No Access

    Article

    Nicorandil suppressed myocardial purine metabolism during exercise in patients with angina pectoris

    To elucidate the effect of Nicorandil on myocardial energy metabolism and myocardial sympathetic activity, we administered Nicorandil orally to eight patients with angina pectoris prior to exercise testing. Ar...

    K. Ogino, S. Osaki, N. Noguchi, H. Kitamura… in European Journal of Clinical Pharmacology (1995)