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Article
Knockdown of Efp by DNA-modified small interfering RNA inhibits breast cancer cell proliferation and in vivo tumor growth
The estrogen-responsive gene Efp promotes the growth of breast cancer cells by stimulating the degradation of a negative cell-cycle regulator, 14-3-3σ, and is hence considered a suitable molecular target for b...
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Chapter and Conference Paper
Smoothed Particle Hydrodynamics with Parallel Virtual Machine
We have developed Remote-GRAPE, a subroutine library to use the special purpose computer GRAPE-3A. It allows us to run applications which use GRAPE-3A hardware on the significantly faster computers than the ph...
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Chapter and Conference Paper
Neuromagnetic Identification of the Somatosensory Cortex in Cases with Arteriovenous Malformation Adjacent to the Central Sulcus
It is critical to preserve eloquent cortices during surgery of cerebral arteriovenous malformations (AVMs). Although MRI scans may identify “anatomical” central suclus, it is controversial whether the “functio...
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Chapter and Conference Paper
Normalized N100m Latency of the Auditory Evoked Fields After Surgical Removal of Temporal Lobe Gliomas
Auditory evoked potentials have been measured in patients with several temporal lobe diseases. The N100 responses disappear in patients with lesions on bilateral superior temporal gyrus[1]. However, separation...
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Chapter and Conference Paper
An Estimation Algorithm of Neuromagnetic Source Using MRI Information
Recently, the imaging technique of the brain function by using the SQUID technology has been developed since technical advancements of the SQUID make it possible to measure feeble magnetic fields of the brain ...
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Chapter and Conference Paper
Visual Evoked Fields for Pattern Reversal Stimuli in Patients with Occipital Lobe Lesions
The “cruciform model” of the visual cortex suggests that the P100 generators of the visual evoked responses to pattern reversal (PR) stimuli are located throughout the entire striate cortex, including the inte...
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Chapter and Conference Paper
Evoked Magnetic Fields for Gustatory Stimuli on the Tongue
Animal studies have suggested that gustatory information primarily projects to the bilateral frontal opercula and dorsal insulae [1,2,3]. However, clinical studies showed that lesions at the postcentral gyrus ...
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Chapter and Conference Paper
Visual Evoked Magnetic Fields: Bilateral Dipole Pattern for Full-Field Stimuli
Pattern reversal stimulus is most frequently used for clinical application of visual evoked potentials (VEPs). Half-field stimulus has been employed to separate the left and right hemispheric responses. In the...
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Chapter and Conference Paper
Effect of Color on Visual Evoked Magnetic Fields with Pattern-Reversal Stimulation
Visual image is supposed to be processed by parallel pathways that analyze different properties of vision such as form, depth, motion, and color. Positron emission tomography (PET) studies of functional specia...
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Chapter and Conference Paper
Origin of Slow Wave Observed in Cerebrovascular Disease
Due to excellent spatio temporal resolution and noninvasive nature of the measurements, magnetoencephalography (MEG) becomes a powerful tool for clinical application. This is especially the case in evoked MEG ...
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Chapter and Conference Paper
MEG: Clinical Applications
During the last two decades, magnetoencephalography (MEG) has become available for monitoring human cortical activity. Although impressive results have been obtained with instruments having smaller coverage, n...
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Chapter and Conference Paper
Parallel Particle Simulations
In these days, demands of more powerful computers in astrophysics is getting harder and harder. One inexpensive way to satisfy such demands is using many computers in parallel. In this paper, we present our pa...
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Chapter and Conference Paper
The Forest Method as a New Parallel Tree Method
Dark matter and stars are collisionless in galaxies and larger systems, and the evolution of a galaxy system consisting of such particles can be studied using an N-body simulation. There are many algorithms propo...
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Chapter
Type Ib-Ic-IIb-IIL Supernovae: Common Envelope Evolution, Instabilities, and Circumstellar Interaction
The origin of an observational diversity of supernova types, namely, Type Ia, Ib, Ic, II-P, II-L, IIb, and IIn, has not been well understood. We propose a new scenario that explains how such a diversity can re...
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Chapter
Type Ia Supernovae: Nucleosynthesis and Constraints on Progenitors
Among the major uncertainties involved in the Chandrasekhar mass models for Type Ia supernovae (SNe Ia) are the companion star of the accreting white dwarf (or the accretion rate that determines the carbon ign...
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Chapter and Conference Paper
Stereotactic Endoscopic Resection of Angiographically Occult Vascular Malformations
Total resection of angiographically occult vascular malformations was performed in four patients using stereotactic open-system endoscopy. The lesions were relatively small but localized deep in the brain or i...