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Article
Synthesis of O-(1′-[18F]fluoropropan-2′-yl)-l-tyrosine (1-[18F]FPT) via Ni(II) complex of (S) tyrosine schiff’s base precursor
O-(1′-[18F]fluoropropan-2′-yl)-l-tyrosine (1-[18F]FPT) was synthesized using the Ni(II)-(S)-[N-2-(N′-benzylprolyl)amino]benzophenone-S-tyrosine based precursor. The precursor was synthesized through a two-step pr...
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Article
Fully automated synthesis of O-(2′-[18F]fluoroethyl)-l-tyrosine ([18F]FET) using solid phase extraction (SPE) purification with neutral alumina
[18F]FET was synthesized using O-(2′-tosyloxyethyl)-N-trityl-l-tyrosine-tert-butyl ester (TET) precursor. SPE purification of [18F]FET, after radio-synthesis, using neutral alumina column was satisfactory, with r...
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Article
Atoms in molecules: Application to electronic structure of van der Waals complexes
Systematic investigation has been carried out to calculate critical points, charge density,ρ(r c), and Laplacian of charge density, ∇2 ρ(r c), for weak complexes in the framework of MP2 and density functional the...