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  1. Article

    Open Access

    Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

    A subset of human hepatocellular carcinomas (HCC) exhibit mutations of β-catenin gene CTNNB1 and overexpress Glutamine synthetase (GS). The CTNNB1-mutated HCC cell line HepG2 is sensitive to glutamine starvation ...

    M Chiu, S Tardito, S Pillozzi, A Arcangeli, A Armento in British Journal of Cancer (2014)

  2. Article

    Open Access

    ERCC1/BRCA1 expression and gene polymorphisms as prognostic and predictive factors in advanced NSCLC treated with or without cisplatin

    The FAST was a factorial trial in first-line treatment of advanced non-small-cell lung cancer (NSCLC), addressing the role of replacing cisplatin with a non-platinum agent. The prognostic and predictive effect...

    M Tiseo, P Bordi, B Bortesi, L Boni, C Boni, E Baldini in British Journal of Cancer (2013)

  3. Article

    Open Access

    Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy

    We analysed the expression of microsatellite instability, p53, p21, vascular endothelial growth factor and thymidylate synthase (TS) in pretreatment biopsy specimens from 57 locally advanced rectal cancers. Th...

    F V Negri, N Campanini, R Camisa, F Pucci, S Bui, G Ceccon in British Journal of Cancer (2008)