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Article
Open AccessClassification of dog skin diseases using deep learning with images captured from multispectral imaging device
Dog-associated infections are related to more than 70 human diseases. Given that the health diagnosis of a dog requires expertise of the veterinarian, an artificial intelligence model for detecting dog disease...
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Article
Open AccessSemi-automated approach for generation of biological networks on drug-induced cholestasis, steatosis, hepatitis, and cirrhosis
Drug-induced liver injury (DILI) is one of the leading reasons for discontinuation of a new drug development project. Diverse machine learning or deep learning models have been developed to predict DILI. Howev...
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Article
Open AccessAcetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives isolated from Castanopsis cuspidata var. sieboldii
Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel acetylcholinesterase (AChE) inhibitors. Five compounds were isolated fr...
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Article
Open AccessAcetylcholinesterase and butyrylcholinesterase inhibitory activities of khellactone coumarin derivatives isolated from Peucedanum japonicum Thurnberg
Cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors have been attracted as candidate treatments for Alzheimer's disease (AD). Fifteen khellactone-type coumarins from the roots of Peucedanum japonicum Thun...
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Article
Open AccessStudy of a BALB/c Mouse Model for Allergic Asthma
Allergic asthma is a worldwide public health problem and a major socioeconomic burden disease. It is a chronic inflammatory disease marked by airway eosinophilia and goblet cell hyperplasia with mucus hypersec...