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  1. Article

    Open Access

    Investigating human-derived lactic acid bacteria for alcohol resistance

    Excessive alcohol consumption has been consistently linked to serious adverse health effects, particularly affecting the liver. One natural defense against the detrimental impacts of alcohol is provided by alc...

    Sini Kang, **g Long, Myeong Soo Park, Geun Eog Ji, Ying Ju in Microbial Cell Factories (2024)

  2. Article

    Open Access

    Faecalibacterium prausnitzii alleviates inflammatory arthritis and regulates IL-17 production, short chain fatty acids, and the intestinal microbial flora in experimental mouse model for rheumatoid arthritis

    Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease that leads to joint destruction and functional disability due to the targeting of self-antigens present in the synovium, cartilage, and bone...

    Jeonghyeon Moon, A. Ram Lee, Heejung Kim, JooYeon Jhun in Arthritis Research & Therapy (2023)

  3. No Access

    Article

    In vivo functional effects of Weissella confusa VP30 exopolysaccharides on loperamide-induced constipation in rats

    In this work, the in vivo functionalities of milk fermented with Weissella confusa VP30 (VP30-EPS) and purified exopolysaccharide (pEPS) from the milk fermented with Weissella confusa VP30 were evaluated for thei...

    Se-Ho Park, Mi-Ra Lee, Su Young Yang, Ju Yeon Lee in Food Science and Biotechnology (2022)

  4. Article

    Open Access

    A recombinant Bifidobacterium bifidum BGN4 strain expressing the streptococcal superoxide dismutase gene ameliorates inflammatory bowel disease

    Inflammatory bowel disease (IBD) is a gastrointestinal disease characterized by diarrhea, rectal bleeding, abdominal pain, and weight loss. Recombinant probiotics producing specific proteins with IBD therapeut...

    Sini Kang, Zhaoyan Lin, Yang Xu, Minju Park, Geun Eog Ji in Microbial Cell Factories (2022)

  5. Article

    Open Access

    Antibacterial effect of cell-free supernatant fraction from Lactobacillus paracasei CH88 against Gardnerella vaginalis

    Bacterial vaginosis (BV) is the most common vaginal infection in reproductive women, which is characterized by depleted level of lactic acid bacteria and overgrowth of anaerobes such as Gardnerella vaginalis spp....

    Eun Chae Moon, Myeong Soo Park, Taehwan Lim, Ryun Hee Kim in Scientific Reports (2022)

  6. No Access

    Article

    Isolation, Characterization and Biosafety Evaluation of Lactobacillus Fermentum OK with Potential Oral Probiotic Properties

    It has been reported that certain probiotic bacteria have inhibitory effects against oral pathogens. Lactobacillus spp. have been studied and used as probiotics globally, but due to difficulties with laboratory c...

    Soyon Mann, Myeong Soo Park, Tony V. Johnston in Probiotics and Antimicrobial Proteins (2021)

  7. Article

    Open Access

    Oral probiotic activities and biosafety of Lactobacillus gasseri HHuMIN D

    Lactobacillus spp. have been researched worldwide and are used in probiotics, but due to difficulties with laboratory cultivation of and experimentation on oral microorganisms, there are few reports of Lactobacil...

    Soyon Mann, Myeong Soo Park, Tony V. Johnston, Geun Eog Ji in Microbial Cell Factories (2021)

  8. Article

    Open Access

    Production of biologically active human interleukin-10 by Bifidobacterium bifidum BGN4

    Bifidobacterium spp. are representative probiotics that play an important role in the health of their hosts. Among various Bifidobacterium spp., B. bifidum BGN4 exhibits relatively high cell adhesion to colonic c...

    Nayoun Hong, Seockmo Ku, Kyung** Yuk, Tony V. Johnston in Microbial Cell Factories (2021)

  9. Article

    Open Access

    Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cells

    To evaluate the immunomodulatory effect of Lactobacillus sakei in a mouse model of rheumatoid arthritis (RA) and in human immune cells.

    Jooyeon Jhun, Hong Ki Min, Jaeyoon Ryu, Seon-Yeong Lee in Journal of Translational Medicine (2020)

  10. No Access

    Article

    Probiotic treatment induced change of inflammation related metabolites in IBS-D patients/double-blind, randomized, placebo-controlled trial

    There have been many studies suggesting that probiotics are effective in patients with diarrhea-predominant irritable bowel syndrome (IBS-D). However, its mechanism of action as well as prediction of response ...

    **joo Kim, Kumsun Cho, Joo Sung Kim, Hyun Chae Jung in Food Science and Biotechnology (2020)

  11. No Access

    Article

    Enzymatic synthesis of β-galactosyl fucose using recombinant bifidobacterial β-galactosidase and its prebiotic effect

    Breast-fed infants have Bifidobacterium-rich gut microbiota compared to infants fed formula. Fucosylated oligosaccharides are the major components of human milk oligosaccharide (HMO) which confer various benefici...

    So-Young Oh, Myeong-Soo Park, Yeong-Geun Lee, Nhan Nguyen Thi in Glycoconjugate Journal (2019)

  12. No Access

    Article

    A review of the internal forced convective heat transfer characteristics of nanofluids: Experimental features, mechanisms and thermal performance criteria

    In this review paper, we summarize important milestones in experimental studies that indicate the effects of volume fraction, nanoparticle size, operating temperature and pH on the internal forced convective h...

    Tae Jong Choi, Bimal Subedi, Hyun Jun Ham in Journal of Mechanical Science and Technolo… (2018)

  13. Article

    Open Access

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin in World Allergy Organization Journal (2016)

  14. Article

    Open Access

    Effects of ascorbic acid on α-l-arabinofuranosidase and α-l-arabinopyranosidase activities from Bifidobacterium longum RD47 and its application to whole cell bioconversion of ginsenoside

    Bifidobacterium longum RD47 was cultured in 24 kinds of modified MRS broths containing various ingredients to select the most promising source that induces microbial enzymes. Among the va...

    Seockmo Ku, Hyun Ju You, Myeong Soo Park in Journal of the Korean Society for Applied … (2015)

  15. No Access

    Article

    Production of γ-aminobutyric acid during fermentation of Gastrodia elata Bl. by co-culture of Lactobacillus brevis GABA 100 with Bifidobacterium bifidum BGN4

    Gastrodia elata Bl. (GE) is a traditional herbal medicine used for the prevention of cerebrovascular disease and for the regulation of one’s blood pressure. γ-Aminobutyric acid (GABA) is known to...

    Jeong Ah Kim, Myeong Soo Park, Soon Ah Kang, Geun Eog Ji in Food Science and Biotechnology (2014)

  16. No Access

    Article

    Effects of phosphorylated cross-linked resistant corn starch on the intestinal microflora and short chain fatty acid formation during in vitro human fecal batch culture

    Changes in the intestinal microflora and formation of short chain fatty acids (SCFAs) were studied in an in vitro human fecal batch culture in a medium containing 10mg/mL of phosphorylated cross-linked resistant ...

    Chun-Ho Bae, Myeong-Soo Park, Geun-Eog Ji, Heui-Dong Park in Food Science and Biotechnology (2013)

  17. No Access

    Article

    Novel Bifidobacterium promoters selected through microarray analysis lead to constitutive high-level gene expression

    For the development of a food-grade expression system for Bifidobacterium, a strong promoter leading to high-level expression of cloned gene is a prerequisite. For this purpose, a promoter screening host-vector s...

    Yan Wang, ** Yong Kim, Myeong Soo Park, Geun Eog Ji in Journal of Microbiology (2012)

  18. No Access

    Article

    Cloning and expression of β-glucosidases from Bifidobacterium lactis AD011

    For the conversion of β-glycosides, 3 genes (BLA_0039, BLA_0141, and BLA_0893) annotated as β-glucosidase (E.C 3.2.1.21) from the genome of Bifidobacterium lactis AD011 were cloned and expressed both in Escherich...

    ** Yong Kim, Yan Wang, Su Ji Park, Geun Eog Ji in Food Science and Biotechnology (2012)

  19. No Access

    Article

    Whole cell biotransformation of major ginsenosides using Leuconostocs and Lactobacilli

    Various strains of Lactobacillus and Leuconostoc species were evaluated to select the most promising strain to carry out transforming major ginsenosides into minor ginsenosides. Among the experimental lactic acid...

    Su Ji Park, So Youn Youn, Geun Eog Ji, Myeong Soo Park in Food Science and Biotechnology (2012)

  20. No Access

    Article

    Clinical Effects of Probiotics are Associated with Increased Transforming Growth Factor-β Responses in Infants with High-Risk Allergy

    We recently demonstrated that the administration of probiotics resulted in a significantly reduced occurrence of atopic dermatitis in infants with high allergic risk. Therefore, the underlying immunological ef...

    Ji Yeun Kim, Young Ok Choi, Jung Hyun Kwon in Journal of the Korean Society for Applied … (2011)

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