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Article
A role for SHPS-1/SIRPα1 in IL-1β- and TNFα-dependent signaling
We investigated the role of SHPS-1/SIRPα1 in IL-1β- and TNFα-dependent signaling that leads to the activation of Erk 1/2 and Akt. Treatment of Balb3T3 cells with IL-1β or TNFα activated tyrosine phosphorylatio...
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Article
Cysteine residues in the C-terminal lobe of Src: their role in the suppression of the Src kinase
To evaluate the function of cysteine residues of the Src kinase, we constructed a series of Src mutants in which some of cyteines were replaced to alanines. With these mutants, we studied the effect of SH-alky...