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    Article

    Evaluating the Effectiveness and Safety of Evinacumab in Treating Hypercholesterolemia and Hypertriglyceridemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

    Cardiovascular disease remains a significant global health concern, with high low-density lipoprotein cholesterol (LDL-C) levels contributing to an increased risk. Familial hypercholesterolemia (FH) further co...

    Hussain Sohail Rangwala, Hareer Fatima in American Journal of Cardiovascular Drugs (2024)

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    Article

    The impact of ketogenic diet on drug-resistant epilepsy in children: A comprehensive review and meta-analysis

    The ketogenic diet (KD), characterized by high-fat and low-carbohydrate intake, is currently gaining widespread popularity as a treatment for drug-resistant epilepsy (DRE). In addition to the traditional ketog...

    Muhammad Saqlain Mustafa in Irish Journal of Medical Science (1971 -) (2024)

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    Article

    Evaluating the effectiveness and safety of various Tirzepatide dosages in the management of Type 2 diabetes mellitus: a network meta-analysis of randomized controlled trials

    Excess body fat, insulin resistance, and abnormal lipid levels signal type 2 diabetes mellitus (DM2). Globally, 536.6 million people suffer from DM2, projected to rise to 783.2 million by 2045. Obesity fuels i...

    Hussain Sohail Rangwala, Hareer Fatima in Journal of Diabetes & Metabolic Disorders (2024)

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    Article

    Evaluating the efficacy and safety of weekly Insulin Icodec vs. Daily Insulin Glargine in type 2 Diabetes Mellitus: a systematic review and meta-analysis

    Various insulin therapies for Diabetes Mellitus offer different benefits while having potential risks. We aim to compare Insulin Icodec, a novel Insulin analogue with the ease of once-weekly administration, to...

    Varisha Zuhair, Muhammad Adil Obaid in Journal of Diabetes & Metabolic Disorders (2024)

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    Article

    Surgical strategies in acute subdural hematoma: a meta-analysis of decompressive craniectomy vs. craniotomy

    Acute subdural hematoma (ASDH) stands as a significant contributor to morbidity after severe traumatic brain injuries (TBI). The primary treatment approach for patients experiencing progressive neurological de...

    Muhammad Ashir Shafique, Muhammad Saqlain Mustafa in Acta Neurochirurgica (2024)

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    Article

    Effectiveness of gamma knife radiosurgery in the management of trigeminal neuralgia associated with multiple sclerosis: a systematic review and meta-analysis

    Trigeminal neuralgia (TN) is a chronic condition characterized by intense facial pain akin to electric shocks, often associated with the trigeminal nerve. It can be either idiopathic or secondary, with multipl...

    Syed Muhmmad Sinaan Ali, Muhammad Ashir Shafique in Neurosurgical Review (2023)

  7. Article

    Open Access

    Subdural evacuating port system for chronic subdural hematoma: a systematic review and meta-analysis of clinical outcomes

    Chronic subdural hematoma (cSDH) is a collection of old blood in the subdural space and has a relatively high estimated incidence, especially among the elderly and men, possibly due to falls, anticoagulant use...

    Muhammad Ashir Shafique, Muhammad Saqlain Mustafa in Egyptian Journal of Neurosurgery (2023)

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    Article

    Letter to the editor: Use of dyna-computed tomography-assisted neuro endoscopic hematoma evacuation in the treatment of hypertensive intracerebral hemorrhage

    Anfal Munir Chaudhary, Afia Fatima, Muhammad Saqlain Mustafa in Neurosurgical Review (2023)

  9. Article

    Open Access

    Ultrasound renal denervation: the future of hypertension management?

    Hypertension, a leading cause of global mortality and morbidity, affects approximately 1.28 billion adults worldwide, with most cases occurring in low- and middle-income countries. Despite several methods for ...

    Laiba Ali, Hareer Fatima, Faiza Riaz in The Egyptian Heart Journal (2023)