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  1. Article

    Open Access

    Oncogenic activity of poly (ADP-ribose) glycohydrolase

    Poly (ADP-ribosylation), known as PARylation, is a post-translational modification catalyzed by poly (ADP-ribose) polymerases (PARP) and primarily removed by the enzyme poly (ADP-ribose) glycohydrolase (PARG)....

    Maud Marques, Maika Jangal, Li-Chun Wang, Anna Kazanets… in Oncogene (2019)

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  2. No Access

    Book

    Advances in DNA Repair in Cancer Therapy

    Lawrence Panasci, Raquel Aloyz… in Cancer Drug Discovery and Development (2013)

  3. No Access

    Chapter

    Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses

    Tumor relapse following primary chemotherapy treatment is an omnious event in most cancer patients undergoing treatment and represents a major clinical challenge in part because relapsed tumors often express a...

    Moulay Alaoui-Jamali, Amine Saad, Gerald Batist in Advances in DNA Repair in Cancer Therapy (2013)

  4. No Access

    Article

    Molecular insights on basal-like breast cancer

    Molecular classification of breast cancer (BC) identified diverse subgroups that encompass distinct biological behavior and clinical implications, in particular in relation to prognosis, spread, and incidence ...

    Mev Dominguez Valentin, Sabrina Daniela da Silva… in Breast Cancer Research and Treatment (2012)

  5. No Access

    Book

    Alternative and Complementary Therapies for Cancer

    Integrative Approaches and Discovery of Conventional Drugs

    Moulay Alaoui-Jamali (2010)

  6. No Access

    Chapter

    Overview of Current TCM Practice and Potential Impacts on Conventional Therapies

    The control of cancer progression, relief of pain, and improvement of the quality of life of patients have been continuing endeavours of both traditional and conventional medicine. Amongst various traditional ...

    Moulay Alaoui-Jamali, Rongyao Zhou in Alternative and Complementary Therapies for Cancer (2010)

  7. No Access

    Chapter

    Herbal Product–Drug Interactions from a Pharmacological Perspective

    Herbal products and their constituents can not only have medicinal benefits, but they have the potential to interfere with the therapeutic activity of anticancer agents and exacerbate side effects. This potent...

    Caroline N. Lougheed, Moulay Alaoui-Jamali in Alternative and Complementary Therapies fo… (2010)

  8. No Access

    Article

    Effect of DNA-repair-enzyme modulators on cytotoxicity ofl-phenylalanine mustard andcis-diamminedichloroplatinum (II) in mammary carcinoma cells resistant to alkylating drugs

    We investigated the effect of DNA-repair-enzyme inhibitors onl-phenylalanine mustard (L-PAM) andcis-diamminedichloroplatinum (II) (CDDP) cytotoxicity in rat mammary-carcinoma MatB cells sensitive (WT) and resista...

    Moulay Alaoui-Jamali, Bel-Baraka Loubaba… in Cancer Chemotherapy and Pharmacology (1994)