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Open AccessExosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis
This study aims to investigate the potential anti-inflammatory effects of exosomes engineered to carry super-repressor IκB (Exo-srIκB), an exosome-based NF-κB inhibitor, in the context of RA.
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Open AccessLaser desorption/ionization mass spectrometry of L-thyroxine (T4) using combi-matrix of α-cyano-4-hydroxycinnamic acid (CHCA) and graphene
An optimal combi-matrix for MALDI-TOF mass spectrometry was presented for the analysis of L-thyroxine (T4) in human serum. For the selection of the optimal combi-matrix, several kinds of combi-matrices were prepa...
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Open AccessQuantitative analysis of vitamin D using m/MALDI-TOF mass spectrometry based on a parylene matrix chip
Vitamin D deficiency is associated with various disorders and is diagnosed based on the concentration of 25-hydroxy vitamin D3 (25(OH)D3) in serum. The parylene matrix chip was fabricated to reduce the matrix bac...
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Open AccessQuantitative analysis of galactose using LDI-TOF MS based on a TiO2 nanowire chip
A novel method for quantifying galactose was developed to serve as a newborn screening test for galactosemia using laser desorption/ionization time-of-flight (LDI-TOF) mass spectrometry (MS) with a TiO2 nanowire ...
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Open AccessKey lime (Citrus aurantifolia) inhibits the growth of triple drug resistant Helicobacter pylori
Eradication rate for Helicobacter pylori (H. pylori) has decreased due to antibiotic resistance. Therefore, new strategies are needed to enhance H. pylori eradication, especially for H. pylori with high antibioti...
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Accuracy evaluation of the crop-weather yield predictive models of Italian ryegrass and forage rye using cross-validation
The objective of this study was to evaluate the accuracy of the yield predictive models of Italian ryegrass (IRG, Lolium multiflorum Lam.) and forage rye (FR, Secale cereale L.) reported in previous studies throu...
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Analysis of predictors influencing indeterminate whole-blood interferon-gamma release assay results in patients with rheumatic diseases
Triggers of indeterminate results from interferon-gamma release assays (IGRA) in patients with rheumatic diseases are still elusive. The aim of the present study was to describe predictors of indeterminate re...
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Open AccessMicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis
Gout is characterized by episodes of intense joint inflammation in response to intra-articular monosodium urate monohydrate (MSU) crystals. miR-155 is crucial for the proinflammatory activation of human myeloi...
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A crossover multi-fluid nonrandom lattice fluid model for pure hydrocarbons and carbon dioxide near to and far from the critical region
The multi-fluid nonrandom lattice fluid model with the local composition concept is capable of describing thermodynamic properties for complex systems, but this model cannot represent the singular behavior of ...