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  1. No Access

    Article

    Identification of new insulin growth factor receptor-1 (IGF-1R) inhibitors via exploring ATPas kinase domain of IGF-1R through virtual screening

    Insulin growth factor receptor-1 is a trans-membrane tyrosine kinase receptor that mediates the polypeptide protein hormone insulin growth factor-1, responsible for normal function and growth of human cells. T...

    Mansi Garg, Monika Chauhan, Raj Kumar in Medicinal Chemistry Research (2017)

  2. Article

    A comprehensive review on bioactive fused heterocycles as purine-utilizing enzymes inhibitors

    Purine-utilizing enzymes (PUEs) are involved in the control of biological actions of nitrogen-containing bases, purines and pyrimidines, by participating in their catabolism, and this has made them a topic of ...

    Monika Chauhan, Raj Kumar in Medicinal Chemistry Research (2015)

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    Article

    Molecular docking and biological evaluation of hydroxy-substituted (Z)-3-benzylideneindolin-2-one chalcones for the lead identification as tyrosinase inhibitors

    The increased cases of hyperpigmentation and other related dermatological problems in human beings have led to the development of a number of tyrosinase inhibitors. In the present study, we have used a docking...

    Sharad Kumar Suthar, Vaibhav Aggarwal, Monika Chauhan… in Medicinal Chemistry Research (2015)

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    Article

    A review on pharmacophoric designs of antiproliferative agents

    Past few decades have witnessed the dawn of new diseases in which cancer is a major problem and the race ensued to eradicate cancer by charting out various effective therapeutic regimens. Circumventing resist...

    Anil Rana, Jimi Marin Alex, Monika Chauhan, Gaurav Joshi… in Medicinal Chemistry Research (2015)