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  1. Article

    Open Access

    Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics

    Nasopharyngeal carcinoma (NPC) is a malignant head and neck cancer type with high morbidity in Southeast Asia, however the pathogenic mechanism of this disease is poorly understood. Using integrative pharmacog...

    Ren-Bo Ding, ** Chen, Barani Kumar Rajendran, Xueying Lyu… in Nature Communications (2021)

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  2. Article

    Open Access

    NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation

    BRCA1 mutation carriers have a higher risk of develo** triple-negative breast cancer (TNBC), which is a refractory disease due to its non-responsiveness to current clinical targeted therapies. Using the Slee...

    Kai Miao, Josh Haipeng Lei, Monica Vishnu Valecha, Ai** Zhang… in Nature Communications (2020)

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