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  1. Article

    Open Access

    (R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice

    Chronic social isolation increases the risk of mental health problems, including cognitive impairments and depression. While subanesthetic ketamine is considered effective for cognitive impairments in patients...

    Rei Yokoyama, Yukio Ago, Hisato Igarashi, Momoko Higuchi in Molecular Psychiatry (2024)