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Article

Adenosine inhibits TNFα-induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A_2A receptor signaling

Adenosine causes the anti-inflammatory effect of MTX; however, the contributions of synoviocyte adenosine receptors (AdoRs) are unknown, and matrix metalloproteinase 3 (MMP-3) is released by fibroblast-like sy...

Hiroe Konishi, Shun-En Kanou, Rika Yukimatsu, Mizuki Inui… in Scientific Reports (2022)