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Article
Haplotype analysis with 14 Y-STR loci using 2 multiplex amplification and ty** systems in 2 regional populations in Japan
In this study 14 Y-STR loci (DYS393, DYS19, DYS391, DYS437, DYS435, DYS439, DYS389II, DYS438, DYS436, DYS390, Y-GATA-H4, DYS385, Y-GATA-A7.1 and DYS392) were analysed in 207 Japanese males from Honshu (main i...
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Article
Open AccessSomatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model
A mouse model that recapitulates the human Ewing's sarcoma-specific chromosomal translocation was generated utilizing the Cre/loxP-mediated recombination technique. A cross between Ewsr1-loxP and Fli1-loxP mice a...
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Protocol
Genetically Engineered Mouse Model in Ewing Sarcoma
Modeling Ewing sarcoma is challenging, since overexpression of EWS-FLI1 induces apoptosis and is not sufficient for tumor induction. It is therefore important to obtain the cell-of-origin of Ewing sarcoma that is...
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Article
Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome
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Article
Open AccessASPSCR1::TFE3 orchestrates the angiogenic program of alveolar soft part sarcoma
Alveolar soft part sarcoma (ASPS) is a soft part malignancy affecting adolescents and young adults. ASPS is characterized by a highly integrated vascular network, and its high metastatic potential indicates th...
