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Article
Open AccessDouble-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells
Triggering receptors expressed on myeloid cells (Trem) proteins are a family of cell surface receptors used to control innate immune responses such as proinflammatory cytokine production in mice. Trem genes be...
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Article
Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis
Genome and expressed sequence tag information of Xenopus tropicalis suggested that short-consensus repeat (SCR)-containing proteins are encoded by three genes that are mapped within a 300-kb downstream of PFKFB2,...
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Article
Phylogenetic and expression analysis of amphibian Xenopus Toll-like receptors
An anuran amphibian, South African clawed frog (Xenopus laevis), is used to study the immune system, as it possesses a set of acquired immune system represented by T and B lymphocytes and ...
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Article
Prediction of the prototype of the human Toll-like receptor gene family from the pufferfish, Fugu rubripes, genome
The insect Toll family of proteins and their mammalian counterparts seemingly shared one common ancestor and evolved independently. Here we demonstrated that the prototype of the mammalian-type (M-type) Toll f...