4 Result(s)
within
Minzhe Guo
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessIdentification of endothelial and mesenchymal FOXF1 enhancers involved in alveolar capillary dysplasia
Mutations in the FOXF1 gene, a key transcriptional regulator of pulmonary vascular development, cause Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins, a lethal lung disease affecting newborns an...
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Article
Open AccessGuided construction of single cell reference for human and mouse lung
Accurate cell type identification is a key and rate-limiting step in single-cell data analysis. Single-cell references with comprehensive cell types, reproducible and functionally validated cell identities, an...
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Article
Open AccessSingle cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth
The respiratory system undergoes a diversity of structural, biochemical, and functional changes necessary for adaptation to air breathing at birth. To identify the heterogeneity of pulmonary cell types and dyn...
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Article
Open AccessSOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma
Since the SOX2 amplification was identified in lung squamous cell carcinoma (lung SCC), SOX2 transcriptional downstream targets have been actively investigated; however, such targets are often cell line specific....
