-
Article
Open AccessPHGDH: a novel therapeutic target in cancer
Serine is a key contributor to the generation of one-carbon units for DNA synthesis during cellular proliferation. In addition, it plays a crucial role in the production of antioxidants that prevent abnormal p...
-
Article
Investigation of Carburization and Melting Behavior of Fully Reduced LRI and IOS on Coke Substrates
In the course of develo** hydrogen-enriched blast furnace ironmaking operation, the carburization and melting behavior of the fully reduced low-reduced iron (LRI) and the iron ore sinter (IOS) on the coke su...
-
Article
Correction: Rapid multi-material joining via flow drill screw process: experiment and FE analysis using the coupled Eulerian‒Lagrangian method
-
Article
Open AccessCharacterization of Formed TRIP1180 Steel Sheet Surface After Stam** with PVD-Coated Tools
The wear tests are conducted on bending punches deposited with PVD CrN and AlTiCrN coatings using the newly proposed progressive die. Then, the surface quality of the formed product is characterized through th...
-
Article
Open AccessBRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with inferior outcomes owing to its low treatment response and high invasiveness. Based on abundant cancer-associated fibroblasts (CA...
-
Article
A Stepped Mesh Host for Lithium Metal Batteries Inspired by Transmission Electron Microscopy Sampling Grids
With the growing demand for high-energy-density rechargeable batteries, lithium metal anodes have reemerged as a promising alternative to conventional graphite anodes in lithium-ion batteries. Lithium metal bo...
-
Article
Fractional Helly Theorem for Cartesian Products of Convex Sets
Helly’s theorem and its variants show that for a family of convex sets in Euclidean space, local intersection patterns influence global intersection patterns. A classical result of Eckhoff in 1988 provided an ...
-
Article
Rapid multi-material joining via flow drill screw process: experiment and FE analysis using the coupled Eulerian‒Lagrangian method
This paper is concerned with experiments and finite element (FE) simulations using the coupled Eulerian‒Lagrangian (CEL) method for multi-material joining by the flow drill screw (FDS) process. The FDS joining...
-
Article
Open AccessLeray Numbers of Tolerance Complexes
Let K be a simplicial complex on vertex set V. K is called d-Leray if the homology groups of any induced subcomplex of K are trivial in dimensions d and higher. K is called d-collapsible if it can be reduced to t...
-
Article
Open AccessCo-inhibition of glutaminolysis and one-carbon metabolism promotes ROS accumulation leading to enhancement of chemotherapeutic efficacy in anaplastic thyroid cancer
Anaplastic thyroid cancer (ATC) is one of the most aggressive tumors with an extremely poor prognosis. Based on the several biological features related to glutamine metabolism in ATC, we hypothesized glutamino...
-
Article
Macroeconomic Effects of COVID-19 Across the World Income Distribution
The macroeconomic effects of the COVID-19 pandemic were most severe for emerging market economies, representing the middle of the world income distribution. This paper provides a quantitative economic theory f...
-
Article
Open AccessUnsupervised anomaly detection for posteroanterior chest X-rays using multiresolution patch-based self-supervised learning
The demand for anomaly detection, which involves the identification of abnormal samples, has continued to increase in various domains. In particular, with increases in the data volume of medical imaging, the d...
-
Article
Quantitative Evaluation of Tool Wear in Cold Stam** of Ultra-High-Strength Steel Sheets
The body of an automobile must be lightweight and crash-worthy. The use of advanced high-strength steel reduces the manufacturing cost for automobile body and improves energy absorption during an impact. Howev...
-
Article
Open AccessWireless dielectrophoresis trap** and remote impedance sensing via resonant wireless power transfer
Nearly all biosensing platforms can be described using two fundamental steps—collection and detection. Target analytes must be delivered to a sensing element, which can then relay the transduced signal. For po...
-
Article
Evaluation of deformation for titanium alloy sheet in single point incremental forming based on asymmetric yield function
This paper is concerned with evaluation of deformation in single point incremental forming (SPIF) for a Ti6Al4V sheet. Tension and compression properties were experimentally obtained along the RD, DD, and TD t...
-
Article
Recent Developments and Trends in Flexible Forming Technology
Flexible metal forming processes are novel ways to meet the growing needs for maintaining economic feasibility in mass production and customization. The flexible forming processes inherently have more process ...
-
Article
Complexes of graphs with bounded independence number
Let G = (V, E) be a graph and n a positive integer. Let In(G) be the abstract simplicial complex whose simplices are the subsets of V that do not contain an independent set of size n in G. We study the collapsibi...
-
Chapter and Conference Paper
Strain Rate-Dependent Hardening Behavior of Weld Metal in Laser Welded Blanks with GEN3 AHSS
This paper introduces the effects of the strain rate on the hardening behavior of weld metal . Mini-tensile specimens to characterize the weld properties. Tensile tests were then performed at strain rates...
-
Chapter and Conference Paper
Shape Optimization of a Cruciform-Like Specimen for Combined Tension and Shear Loading
The present work is concerned with the optimization of cruciform-like specimen shape under combined loading. A novel shape of a cruciform-like specimen is proposed, to measure flow stresses under combined ....
-
Article
Open AccessEvaluation of the feasibility of explainable computer-aided detection of cardiomegaly on chest radiographs using deep learning
We examined the feasibility of explainable computer-aided detection of cardiomegaly in routine clinical practice using segmentation-based methods. Overall, 793 retrospectively acquired posterior–anterior (PA) ...
