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Article
Open AccessAn evaluation method of open-pit slope stability based on Poset theory
To achieve an objective and reasonable judgment on slope stability, the partially ordered set (Poset) theory is applied to the slope stability evaluation against the engineering background of an open pit slope...
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Article
Impact of COVID-19 on HIV Prevention Access: A Multi-platform Social Media Infodemiology Study
This study seeks to identify and characterize key barriers associated with PrEP therapy as self-reported by users on social media platforms. We used data mining and unsupervised machine learning approaches to ...
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Article
Open AccessStudy on web pillar failure mechanism during auger mining and its associated risk assessment
To safely and efficiently recover trapped coal under final endwalls in open cut mines, theoretical analysis and numerical calculation were used to study the stability of web pillar during auger mining. The par...
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Article
Open AccessExploring substance use disorder discussions in Native American communities: a retrospective Twitter infodemiology study
The opioid epidemic has had a devastating impact on youth from American Indian and Alaska Native (AI/AN) Tribes and Villages, which also experience disparate suicide rates. The use of publicly available social...
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Article
Integrating the LSSVM and RBFNN models with three optimization algorithms to predict the soil liquefaction potential
Liquefaction has caused many catastrophes during earthquakes in the past. When an earthquake is occurring, saturated granular soils may be subjected to the liquefaction phenomenon that can result in significan...
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Article
Open AccessGeneration of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs
Deep learning (DL) is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological data. However, progress in oligopeptide ...
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Article
Open AccessA functional motif of long noncoding RNA Nron against osteoporosis
Long noncoding RNAs are widely implicated in diverse disease processes. Nonetheless, their regulatory roles in bone resorption are undefined. Here, we identify lncRNA Nron as a critical suppressor of bone reso...
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Article
Open AccessA longitudinal and geospatial analysis of COVID-19 tweets during the early outbreak period in the United States
Early reports of COVID-19 cases and deaths may not accurately convey community-level concern about the pandemic during early stages, particularly in the United States where testing capacity was initially limit...
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Article
The long noncoding RNA lnc-ob1 facilitates bone formation by upregulating Osterix in osteoblasts
Long noncoding RNAs (lncRNAs) have emerged as integral regulators of physiology and disease, but specific roles of lncRNAs in bone disease remain largely unknown. Here, we show that lnc-ob1 regulates osteoblas...
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Article
Open AccessLnc-mg is a long non-coding RNA that promotes myogenesis
Recent studies indicate important roles for long noncoding RNAs (lncRNAs) as essential regulators of myogenesis and adult skeletal muscle regeneration. However, the specific roles of lncRNAs in myogenic differ...
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Article
A status report on helium inductively coupled plasma mass spectrometry
The current status of helium inductively coupled plasma – mass spectrometry (He ICPMS) is examined, its potentials and limitations are reviewed, and a summary of fundamental properties of atmospheric pressure ...