-
Article
High expression of CFTR in cumulus cells from mature oocytes is associated with high-quality of oocyte and subsequent embryonic development
The purpose of this study was to explore the association of expression of cystic fibrosis transmembrane conductance regulator (CFTR) in cumulus cells (CCs) from mature oocytes with oocyte quality and embryonic...
-
Article
Open AccessIdentification of the major photodegradant in metronidazole by LC-PDA-MS and its reveal in compendial methods
Metronidazole in aqueous solution is sensitive to light and UV irradiation, leading to the formation of N-(2-hydroxyethyl)-5-methyl-l,2,4-oxadiazole-3-carboxamide. This is revealed here by liquid chromatography w...
-
Article
Open AccessA simple method for HPLC retention time prediction: linear calibration using two reference substances
Analysis of related substances in pharmaceutical chemicals and multi-components in traditional Chinese medicines needs bulk of reference substances to identify the chromatographic peaks accurately. But the ref...
-
Article
Synthesis of mangiferin derivatives as protein tyrosine phosphatase 1B inhibitors
Protein tyrosine phosphatase 1B (PTP1B) has received much attention due to its pivotal role in type 2 diabetes and obesity as a negative regulator of the insulin signaling pathway. Mangiferin, a xanthone gluco...
-
Article
Comparison of Three RP-HPLC Methods for Analysis of Cefpodoxime Proxetil and Related Substances
A comparison of testing methods for analysis of cefpodoxime proxetil and its related substances was performed to determine which available analytical method was most appropriate for quality control. Three RP-H...
-
Article
Analysis of Spectinomycin by HPLC with Evaporative Light-Scattering Detection
A high-performance liquid chromatographic method with evaporative light-scattering detection (ELSD) has been developed for analysis of spectinomycin and related impurities. Separation of spectinomycin from str...
