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Article
Open AccessThe N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer
Posttranscriptional modification of tumor-associated factors plays a pivotal role in breast cancer progression. However, the underlying mechanism remains unknown. M6A modifications in cancer cells are dynamic ...
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Article
Open AccessCardiovascular risk factors and breast cancer incidence in a large middle-aged cohort study
Several studies have demonstrated that cardiovascular risk factors play a role in the etiology of breast cancer. However, the combined effect of cardiovascular risk factors on the risk of breast cancer is stil...
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Article
Open AccessThe miR-1185-2-3p—GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1
Phosphatidylinositol-4-phosphate-binding protein GOLPH3L is overexpressed in human ductal carcinoma of the breast, and its expression levels correlate with the prognosis of breast cancer patients. However, the...
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Chapter and Conference Paper
Two-Stage Cascaded U-Net: 1st Place Solution to BraTS Challenge 2019 Segmentation Task
In this paper, we devise a novel two-stage cascaded U-Net to segment the substructures of brain tumors from coarse to fine. The network is trained end-to-end on the Multimodal Brain Tumor Segmentation Challeng...
