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Article
Effects of a hemagglutinin D222G substitution on the pathogenicity of 2009 influenza A (H1N1) virus in mice
The surface glycoprotein hemagglutinin (HA) of influenza virus initiates the infection process by binding to sialic acid receptors on upper respiratory cells in the host. In contrast to avian influenza viruses...
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Article
Open AccessInhibition of Pseudomonas aeruginosa with a recombinant RNA-based viral vector expressing human β-defensin 4
Harassed with extensive epithelial burn wounds, patients can be affected by complications, such as infection, hypovolemic shock, hypothermia, and respiratory failure. Immediate first aid and followed supportiv...
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Article
DBA/2 mouse as an animal model for anti-influenza drug efficacy evaluation
Influenza viruses are seasonally recurring human pathogens. Vaccines and antiviral drugs are available for influenza. However, the viruses, which often change themselves via antigenic drift and shift, demand c...
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Article
The anti-influenza virus effect of Phellinus igniarius extract
Herbal medicine has been used in the orient for thousands of years to treat large and small ailments, including microbial infections. Although there are treatments for influenza virus infection, there is no tr...
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Article
Susceptibility of human H3N2 influenza virus to oseltamivir in South Korea, 2009–2011
During the 2009–2011 influenza seasons, 10.26% of the specimens isolated from patients in South Korea were subtyped as H3N2 viruses. Some oseltamivir-sensitive H3N2 samples exhibited different plaque morpholog...
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Article
GFP-expressing influenza a virus for evaluation of the efficacy of antiviral agents
To address its value as a screening tool in the development of antiviral drugs, a recombinant influenza virus expressing green fluorescent protein (rPR8-GFP virus) was investigated in vitro and in vivo. The inhib...
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Chapter and Conference Paper
Evolutionary learning algorithm for projection neural networks
This paper proposes an evolutionary learning algorithm to discipline the projection neural networks (PNNs) which can activate radial basis functions as well as sigmoid functions with special type of hidden nod...
