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  1. No Access

    Article

    Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer

    Hypoxia, or the deficiency of oxygen, in solid tumors is majorly responsible for the progression of cancer and remains unaffected by chemotherapy, but still requires definitive definition of the hypoxia signal...

    Seong Hye Park, Soyeon Jeong, Bo Ram Kim, Yoon A Jeong, Jung Lim Kim… in Oncogene (2020)

  2. Article

    Open Access

    Genipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer

    Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relat...

    Min Jee Jo, Soyeon Jeong, Hye Kyeong Yun, Dae Yeong Kim, Bo Ram Kim… in BMC Cancer (2019)

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  3. No Access

    Article

    RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer

    RUNX3 is frequently inactivated by DNA hypermethylation in numerous cancers. Here, we show that RUNX3 has an important role in modulating apoptosis in immediate response to tumor necrosis factor-related apopto...

    Bo Ram Kim, Seong Hye Park, Yoon A Jeong, Yoo ** Na, Jung Lim Kim, Min Jee Jo… in Oncogene (2019)