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Article

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries

Polygenic risk scores (PRS) are valuable to translate the results of genome-wide association studies (GWAS) into clinical practice. To date, most GWAS have been based on individuals of European-ancestry leadin...

Yanyu Liang, Milton Pividori, Ani Manichaikul, Abraham A. Palmer… in Genome Biology (2022)