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Article
Population-based investigation of relative clearance of digoxin in Japanese neonates and infants by multiple-trough screen analysis
Objective: The steady-state concentrations of digoxin at trough levels were studied to establish the role of patient characteristics in estimating doses for digoxin using routine therapeutic dru...
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Article
Population Pharmacokinetics of Digoxin in Japanese Patients
To clarify the observed variability of digoxin disposition by performing a population pharmacokinetic analysis in a Japanese population.
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Article
Population Pharmacokinetics of Haloperidol Using Routine Clinical Pharmacokinetic Data in Japanese Patients
To clarify the observed variability of haloperidol disposition in patients with psychiatric disorders.
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Article
Determination of Digoxin Clearance in Japanese Elderly Patients for Optimization of Drug Therapy
Background: Optimal use of digoxin in the elderly population requires information about the drug’s pharmacokinetics and the influence of various factors on the drug’s disposition. However, becaus...