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Article
Open AccessCulinary continuity in central Japan across the transition to agriculture
Rice and millet arrived in Western Japan from Korea around 3,000 years ago and spread eastwards across the archipelago in the next 700 years. However, the extent to which agriculture transformed traditional Jō...
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Article
Open AccessRelationship between food group-specific intake and depression among local government employees in Japan
We aimed to examine the relationship between food group-specific intake and depression among workers in Japan.
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Article
Impact of the interpregnancy interval after cesarean delivery on subsequent perinatal risks: a retrospective study
To assess the impact of the interpregnancy interval (IPI) after cesarean delivery on the risks of adverse perinatal events during subsequent pregnancies.
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Chapter
West Asia
This chapter presents a brief overview of Middle and Upper Paleolithic sites and lithic assemblages in West Asia as an introduction to relevant records in PaleoAsia DB, which were registered mainly during 2010...
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Chapter
South Asia
This chapter focuses on South Asia, which covers Afghanistan, Pakistan, India, and Sri Lanka. A total of 34 sites and 62 cultural layers are registered on PaleoAsiaDB. The lithic assemblages from 200 to 20 ka ...
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Chapter
Africa
This chapter presents a brief overview of Middle Stone Age (MSA) and Later Stone Age (LSA) sites and lithic assemblages in Africa as an introduction to relevant records in PaleoAsia DB, which were registered m...
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Europe (2)
The western part of Russia, west of the Ural Mountains, is dealt with Europe in the PaleoAsiaDB. A total of 81 and 109 cultural layers are registered for the Middle and Upper Palaeolithic respectively. Despite...
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Chapter
Japanese Archipelago
This chapter provides an overview of the Upper Paleolithic prior to 20 ka in the Japanese Archipelago. In PaleoAsiaDB, 2,427 cultural layers of 1,036 sites are registered under the Japanese Upper Paleolithic. ...
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Chapter
Registered Sites in the PaleoAsiaDB
The full dataset of PaleoAsiaDB is available in an electronic form at UMDB, a database portal of The University Museum, The University of Tokyo, Japan (http://umdb.um.u-tokyo.ac.jp/DKoukoga/
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Article
Open AccessLive imaging of apoptotic signaling flow using tunable combinatorial FRET-based bioprobes for cell population analysis of caspase cascades
Understanding cellular signaling flow is required to comprehend living organisms. Various live cell imaging tools have been developed but challenges remain due to complex cross-talk between pathways and respon...
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Article
Open AccessDeletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice
Aging is considered to be accelerated by insulin signaling in lower organisms, but it remained unclear whether this could hold true for mammals. Here we show that mice with skeletal muscle-specific double knoc...
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Article
Open AccessBoth T cell priming in lymph node and CXCR3-dependent migration are the key events for predicting the response of atezolizumab
Anti-PD-L1 antibodies benefit many cancer patients, even those with “non-inflamed tumor”. Determining which patients will benefit remains an important clinical goal. In a non-inflamed tumor mouse model, we fou...
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Article
Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphoma
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasm. While ATL cells in peripheral blood (PB-ATL) are sensitive to anti-CC chemokine receptor 4 treatment, non–PB-ATLs, including lymph node AT...
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Article
A phase II study of HMB/Arg/Gln against oral mucositis induced by chemoradiotherapy for patients with head and neck cancer
This phase II trial assessed the clinical benefit of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine (HMB/Arg/Gln) for preventing chemoradiotherapy (CRT)-induced oral mucositis (OM) in patients with ...
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Article
Size distribution of allergenic Cry j 2 released from airborne Cryptomeria japonica pollen grains during the pollen scattering seasons
Japanese cedar (Cryptomeria japonica) pollinosis is one of seasonal allergic rhinitis that mainly occurs in Japan. The pollinosis is caused by two main kinds of allergenic proteins called Cry j 1 and Cry j 2 whic...
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Article
Multicenter phase II study of an oral care program for patients with head and neck cancer receiving chemoradiotherapy
This multicenter phase II trial assessed the clinical benefit of a multidisciplinary oral care program in reducing the incidence of severe chemoradiotherapy-induced oral mucositis (OM).
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Article
Precise Fractionation of CdSe/ZnS Quantum Dot-Organic-Dye Conjugates Using a Gel Filtration Column
Conjugates of semiconductor quantum dots (QDs) and organic dyes have been receiving attention as fluorescence biological sensing materials. In designing such sensors, a most important parameter is the number o...
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Article
Open AccessEstablishment of a reborn MMV-microarray technology: realization of microbiome analysis and other hitherto inaccessible technologies
With the accelerating development of bioscience, the problem of research cost has become important. We previously devised and developed a novel concept microarray with manageable volumes (MMV) using a soft gel...
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Article
CdSe/ZnS Quantum Dots Conjugated with a Fluorescein Derivative: a FRET-based pH Sensor for Physiological Alkaline Conditions
Dual pH-dependent fluorescence peaks from a semiconductor quantum dot (QD) and a pH-dependent fluorescent dye can be measured by irradiating with a single wavelength light, and the pH can be estimated from the...
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Article
Open AccessSystematic genome sequence differences among leaf cells within individual trees
Even in the age of next-generation sequencing (NGS), it has been unclear whether or not cells within a single organism have systematically distinctive genomes. Resolving this question, one of the most basic biolo...