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Open AccessEmergence of carbapenem-resistant and colistin-susceptible Enterobacter cloacae complex co-harboring blaIMP-1 and mcr-9 in Japan
The spread of Enterobacteriaceae producing both carbapenemases and Mcr, encoded by plasmid-mediated colistin resistance genes, has become a serious public health problem worldwide. This study describes three clin...
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Article
Chronic inflammatory demyelinating polyneuropathy in adult T-cell leukemia-lymphoma patients following allogeneic stem cell transplantation
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Article
Circulating tumor DNA dynamically predicts response and/or relapse in patients with hematological malignancies
A growing body of evidence suggests that tumor-derived fragmentary DNA, known as circulating tumor DNA (ctDNA), has the potential to serve as a non-invasive biomarker for disease monitoring. However, in the se...
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Article
Functional Salivary Gland Regenerative Therapy for Oral Health
Salivary glands maintain oral health and homeostasis via functional interactions with many organs, including the teeth and the tongue. Dysfunction of salivary glands causes many problems, such as dental caries...
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Article
Molecular analysis of antigenicity and immunogenicity of a vaccine-induced escape mutant of hepatitis B virus
To analyze the mechanisms of mutant escape, we established a murine model of hepatitis B virus (HBV) infection and studied the interaction of the envelope protein of the virion with various kinds of anti-hepa...
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Different antibody responses against hepatitis B surface antigen among mouse strains transfected with mutant viral DNA
Rapid seroconversion from hepatitis B surface antigen (HBsAg) to anti-HBs antibody is seen in most patients with fulminant hepatitis B. It is unclear whether viral mutation or host immune background is respon...
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Article
Small-bowel hemorrhage caused by cytomegalovirus vasculitis following fulminant hepatitis
We describe life-threatening vasculitis of the small bowel following fulminant hepatitis. A 35-year-old man was admitted to our hospital due to consciousness disturbance and jaundice. He was diagnosed with ful...
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Prevalence of herpesviridae and hepatitis virus sequences in the livers of patients with fulminant hepatitis of unknown etiology in Japan
Fulminant non-A, non-B, non-C hepatitis has a high mortality rate, making the identification of its causative agent imperative. Cytomegalovirus, Epstein-Barr virus, human herpesvirus-6, and herpes simplex vir...
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Living-related partial liver transplantation for decompensated hepatitis B without reactivation of hepatitis B in the following 30 months