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  1. No Access

    Protocol

    Generation of Three-Dimensional Retinal Tissue with Physiologically Competent, Light-Sensitive Photoreceptors from Human-Induced Pluripotent Stem Cells

    Human retinal organoids are three-dimensional tissue systems derived from human pluripotent stem cells (hPSCs) that recreate aspects of the cytoarchitectural organization of the retina. The potential of these ...

    Silvia Aparicio-Domingo, Miguel Flores-Bellver, Hannah Cobb… in Brain Organoid Research (2023)

  2. Article

    Open Access

    Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitor cells

    The mechanisms underlying retinal development have not been completely elucidated. Extracellular vesicles (EVs) are novel essential mediators of cell-to-cell communication with emerging roles in developmental ...

    **g Zhou, Miguel Flores-Bellver, Jianbo Pan, Alberto Benito-Martin… in Scientific Reports (2021)

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    Chapter

    Role of Lycium Barbarum Extracts in Retinal Diseases

    Wolfberry (Lycium barbarum) extracts have been used in the treatment of some retinal degenerative diseases, mostly associated with other antioxidants. The ones this chapter focuses on are retinitis pigmentosa and...

    María Benlloch, María Muriach, Gloria Castellano… in Lycium Barbarum and Human Health (2015)