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  1. Article

    Open Access

    Correction to: Predictive risk factors of phenoconversion in idiopathic REM sleep behavior disorder: the Italian study “FARPRESTO”

    Monica Puligheddu, Michela Figorilli, Elena Antelmi, Dario Arnaldi in Neurological Sciences (2023)

  2. No Access

    Chapter

    Autonomic Dysfunction in Sleep Disorders

    The autonomic nervous system (ANS) main function is the maintenance of body homeostasis and the promotion of adaptation against external changes. Sleep state deeply differs from waking state in terms of metabo...

    Marco Bozzali, Raffaele Manni in Autonomic Disorders in Clinical Practice (2023)

  3. No Access

    Chapter

    Autonomic Dysfunctions in Temporal Lobe Epilepsy

    Epilepsy can manifest with a wide range of manifestations, including alterations in the activity of the autonomic nervous system. These are more frequent in focal epilepsies, namely in temporal lobe epilepsy (...

    Michele Terzaghi, Elena Capriglia in Autonomic Disorders in Clinical Practice (2023)

  4. Article

    Open Access

    Predictive risk factors of phenoconversion in idiopathic REM sleep behavior disorder: the Italian study “FARPRESTO”

    Most patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt α-synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from diagnosis. Several markers of phe...

    Monica Puligheddu, Michela Figorilli, Elena Antelmi, Dario Arnaldi in Neurological Sciences (2022)

  5. Article

    Open Access

    Clinical characteristics of a large cohort of patients with narcolepsy candidate for pitolisant: a cross-sectional study from the Italian PASS Wakix® Cohort

    Narcolepsy is a chronic and rare hypersomnia of central origin characterized by excessive daytime sleepiness and a complex array of symptoms as well as by several medical comorbidities. With growing pharmacolo...

    Carlotta Mutti, Valerio Brunetti, Michela Figorilli in Neurological Sciences (2022)

  6. No Access

    Article

    Cuneus/precuneus as a central hub for brain functional connectivity of mild cognitive impairment in idiopathic REM sleep behavior patients

    To investigate brain functional correlates of mild cognitive impairment (MCI) in idiopathic REM sleep behavior disorder (iRBD).

    Pietro Mattioli, Matteo Pardini in European Journal of Nuclear Medicine and M… (2021)

  7. No Access

    Reference Work Entry In depth

    Sleep Disorders and Cardiovascular Disease

    Sleep and heart show a bidirectional relationship, in which sleep disorders influence cardiac function and cardiac pathology may conversely disrupt sleep architecture. Sleep is considered a dynamic process wit...

    Michele Terzaghi, Gianpaolo Toscano, Raffaele Manni in Brain and Heart Dynamics (2020)

  8. No Access

    Reference Work Entry In depth

    Epilepsy and Cardiovascular Function

    Epilepsy is a chronic neurological disorder, characterized by predisposition to recurrent seizures. Epilepsy patients show an increased mortality rate, and cardiovascular disease is a significant cause of death.

    Raffaele Manni, Gianpaolo Toscano, Michele Terzaghi in Brain and Heart Dynamics (2020)

  9. No Access

    Living Reference Work Entry In depth

    Epilepsy and Cardiovascular Function

    Epilepsy is a chronic neurological disorder, characterized by predisposition to recurrent seizures. Epilepsy patients show an increased mortality rate, and cardiovascular disease is a significant cause of death.

    Raffaele Manni, Gianpaolo Toscano, Michele Terzaghi in Brain and Heart Dynamics

  10. No Access

    Chapter

    Differential Diagnosis and Related Disorders: RBD Mimics

    A wide range of motor-behavioral sleep-related events may simulate RBD episodes, leading to RBD misdiagnosis. RBD mimics include arousalrelated motor manifestations in severe obstructive sleep apnea, disorders...

    Raffaele Manni, Michele Terzaghi in Rapid-Eye-Movement Sleep Behavior Disorder (2019)

  11. No Access

    Chapter

    Local Cortical Activations During REM Sleep and Implications for RBD

    Different neuroimaging and intracerebral EEG studies have shown that brain activity during physiologic REM sleep in humans is not temporally and spatially homogeneous. Indeed, some brain regions (i.e., motor c...

    Paola Proserpio, Michele Terzaghi in Rapid-Eye-Movement Sleep Behavior Disorder (2019)

  12. No Access

    Living Reference Work Entry In depth

    Sleep Disorders and Cardiovascular Disease

    Sleep and heart show a bidirectional relationship, in which sleep disorders influence cardiac function and cardiac pathology may conversely disrupt sleep architecture. Sleep is considered a dynamic process wit...

    Michele Terzaghi, Gianpaolo Toscano, Raffaele Manni in Brain and Heart Dynamics

  13. Article

    Disorders of Arousal

    Sleepwalking, sleep terrors, and confusional arousals are non-REM sleep parasomnias grouped under the specific category of disorders of arousal (DOA). These conditions are characterized by incomplete arousals ...

    Andrea Galbiati, Raffaele Manni, Michele Terzaghi in Current Sleep Medicine Reports (2016)

  14. No Access

    Article

    Sleep-Disordered Breathing in Dementia with Lewy Bodies

    Dementia with Lewy bodies (DLB) is the second most common form of dementia, and it is very frequently associated with changes in sleep patterns. To date, the literature has focused mainly on REM sleep behavior...

    Raffaele Manni, Michele Terzaghi in Current Neurology and Neuroscience Reports (2015)

  15. Article

    Erratum to: Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case–control study

    Luigi Ferini-Strambi, Wolfgang Oertel, Yves Dauvilliers in Journal of Neurology (2015)

  16. No Access

    Article

    Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case–control study

    Patients with idiopathic REM sleep behavior disorder (iRBD) are at very high risk of develo** neurodegenerative synucleinopathies, which are disorders with prominent autonomic dysfunction. Several studies ha...

    Luigi Ferini-Strambi, Wolfgang Oertel, Yves Dauvilliers in Journal of Neurology (2014)

  17. No Access

    Chapter

    Pain, Cancer, Fibromyalgia and Gastrointestinal Disorders

    Daytime sleepiness is very frequent in chronic pain sufferers and it is underpinned by disrupted nocturnal sleep patterns as well as by pain medications. There is emerging evidence that sleep disorders and day...

    Raffaele Manni, Riccardo Cremascoli in Sleepiness and Human Impact Assessment (2014)

  18. No Access

    Article

    Sleep paralysis in narcolepsy: more than just a motor dissociative phenomenon?

    Sleep paralyses are viewed as pure motor phenomena featured by a dissociated state in which REM-related muscle atonia coexists with a wakefulness state of full consciousness. We present a 59-year-old man diagn...

    Michele Terzaghi, Pietro Luca Ratti, Francesco Manni in Neurological Sciences (2012)