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Open AccessClinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer
Over the past few years, next-generation sequencing (NGS) has become reliable and cost-effective, and its use in clinical practice has become a reality. A relevant role for NGS is the prediction of response to...
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Open AccessHer2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases
Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) patients. Real-time quantitat...
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Open AccessCTLA-4 checkpoint blockade in breast cancer, a case in point report