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  1. Article

    Open Access

    Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

    Over the past few years, next-generation sequencing (NGS) has become reliable and cost-effective, and its use in clinical practice has become a reality. A relevant role for NGS is the prediction of response to...

    Edoardo Isnaldi, Anna Garuti, Gabriella Cirmena in Journal of Translational Medicine (2019)

  2. Article

    Open Access

    Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases

    Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) patients. Real-time quantitat...

    Gabriele Zoppoli, Anna Garuti, Gabriella Cirmena in Journal of Translational Medicine (2017)

  3. Article

    Open Access

    CTLA-4 checkpoint blockade in breast cancer, a case in point report

    Chiara Dellepiane, Michela Lia in Journal for ImmunoTherapy of Cancer (2015)