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  1. Article

    Erratum to: A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents

    Michal Caspi, Anastasia Firsow, Raja Rajkumar, Nir Skalka in Journal of Molecular Medicine (2016)

  2. No Access

    Article

    A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents

    A large number of human diseases are caused by nonsense mutations. These mutations result in premature protein termination and the expression of truncated, usually nonfunctional products. A promising therapeut...

    Michal Caspi, Anastasia Firsow, Raja Rajkumar, Nir Skalka in Journal of Molecular Medicine (2016)

  3. No Access

    Article

    Serum starvation enhances nonsense mutation readthrough

    Of all genetic mutations causing human disease, premature termination codons (PTCs) that result from splicing defaults, insertions, deletions, and point mutations comprise around 30%. From these mutations, aro...

    Amnon Wittenstein, Michal Caspi, Yifat David, Yamit Shorer in Journal of Molecular Medicine (2019)

  4. Article

    Open Access

    A CRISPR knockout screen reveals new regulators of canonical Wnt signaling

    The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including canc...

    Tamar Evron, Michal Caspi, Michal Kazelnik, Yarden Shor-Nareznoy in Oncogenesis (2021)