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  1. Article

    Open Access

    Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

    Circulating metabolites have been shown to reflect metabolic changes during the development of type 2 diabetes. In this study we examined the association of metabolite levels and pairwise metabolite ratios wit...

    Sophie Molnos, Simone Wahl, Mark Haid, E. Marelise W. Eekhoff, René Pool… in Diabetologia (2018)

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  2. Article

    Open Access

    The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes

    The gut microbiota has been linked to metabolic diseases. However, information on the microbiome of young adults at risk for type 2 diabetes (T2D) is lacking. The aim of this cross-sectional analysis was to in...

    Marina Fugmann, Michaela Breier, Marietta Rottenkolber… in Scientific Reports (2015)

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  3. Article

    Open Access

    Metabolite profiling reveals new insights into the regulation of serum urate in humans

    Serum urate, the final breakdown product of purine metabolism, is causally involved in the pathogenesis of gout, and implicated in cardiovascular disease and type 2 diabetes. Serum urate levels highly differ b...

    Eva Albrecht, Melanie Waldenberger, Jan Krumsiek, Anne M. Evans… in Metabolomics (2014)

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  4. No Access

    Article

    Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children

    The amount of weight loss in obese children during lifestyle intervention differs strongly between individuals. The metabolic processes underlying this variability are largely unknown. We hypothesize that meta...

    Simone Wahl, Christina Holzapfel, Zhonghao Yu, Michaela Breier… in Metabolomics (2013)