31 Result(s)
within
Michael O’Callaghan
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Article
Open AccessSeminal Papers in Urology: Darolutamide and survival in metastatic, hormone-sensitive prostate cancer
The ARASENS trial recruited 1306 men with metastatic hormone sensitive prostate cancer. It investigated the effect of androgen deprivation therapy (ADT) and systemic therapy docetaxel in combination with a thi...
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The association of smoking with urinary and sexual function recovery following radical prostatectomy for localized prostate cancer: a systematic review and meta-analysis
Urinary and sexual dysfunction after radical prostatectomy remains a major cause of morbidity, despite widespread availability of pharmacological and rehabilitative treatments. Smoking is a modifiable risk fac...
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Open AccessSeminal papers in urology: urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study
Kidney stones, a persistent urological condition, continue to affect people globally. In this critical review, we examine the work of Borghi et al. who evaluated patients with idiopathic stone formation and ra...
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Systematic review of the ophthalmic complications of robotic-assisted laparoscopic prostatectomy
This study aims to review ophthalmic injuries sustained during of robotic-assisted laparoscopic prostatectomy (RALP). A search of Medline, Embase, Cochrane and grey literature was performed using methods regis...
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Open AccessSeminal papers in urology: two-year outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for refractory urgency urinary incontinence: a Randomized Trial
In this critical review, we explore the study design, strengths and limitations of the paper: “Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence:...
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Open AccessLength of positive surgical margins after radical prostatectomy: Does size matter? – A systematic review and meta-analysis
The prognostic capacity of positive surgical margins (PSM) for biochemical recurrence (BCR) is unclear, with inconsistent findings across published studies. We aimed to systematically review and perform a meta...
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Open AccessSeminal papers in urology: maintenance Bacillus Calmette-Guerin (BCG) immunotherapy for recurrent Ta, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized southwest oncology group study (SWOG-8507)
The South West Oncology Group’s 2000 randomised-control trial investigated the addition of maintenance intravesical bacillus Calmette-Guerin (BCG) to non-muscle invasive urothelial carcinoma (NMIUC) treatment....
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Open AccessRisk of secondary malignancy following radiation therapy for prostate cancer
We investigated whether prostate cancer patients treated with external beam radiation therapy (EBRT) have a higher cumulative incidence of secondary cancer compared with patients treated with radical prostatec...
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Article
Open AccessResponsiveness and construct validity of EPIC-26, AQoL-6D and SF-6D following treatment in prostate cancer
To assess construct validity and responsiveness of the Expanded Prostate Cancer Index Composite Instrument (EPIC-26) relative to the Short-Form Six-Dimension (SF-6D) and Assessment of Quality of Life 6-Dimensi...
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Open AccessSystematic review of urological injury during caesarean section and hysterectomy
We aim to review iatrogenic bladder and ureteric injuries sustained during caesarean section and hysterectomy.
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PSMA-PET to detect prostate cancer recurrence after radiotherapy
PSA dynamics and conventional imaging methods currently used to assess biochemical recurrence of prostate cancer after definitive treatment with radiotherapy are insufficient, especially considering that diffe...
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Open AccessPatient-reported functional outcome measures and treatment choice for prostate cancer
The aim of this study was to describe changes in patient-reported functional outcome measures (PROMs) comparing pre-treatment and 12 months after radical prostatectomy (RP), external beam radiation therapy (EB...
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Open AccessImpact of different unconditional monetary incentives on survey response rates in men with prostate cancer: a 2-arm randomised trial
Men are often viewed as a difficult group to recruit for psychological research, including in psycho-oncology. Whilst research has demonstrated the effectiveness of small monetary incentives for encouraging re...
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Open AccessProtocol for the Flinders Kidney Health Registry: patient outcomes of kidney cancers and nephrectomies
Kidney cancer accounts for 2% of new cancers diagnosed in Australia annually. Partial and radical nephrectomy are the treatment of choice for kidney cancer. Nephrectomy is also performed for living donor kidne...
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Open AccessEvaluation of selective bone scan staging in prostate cancer – external validation of current strategies and decision-curve analysis
Recommendations for staging newly diagnosed prostate cancer patients vary between guidelines and literature.
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Article
Prostate cancer detection: a systematic review of urinary biosensors
Current diagnostic methods for prostate cancer are invasive and lack specificity towards aggressive forms of the disease, which can lead to overtreatment. A new class of non-invasive alternatives is under deve...
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Open AccessCareer destinations of graduates from a medical school with an 18-week longitudinal integrated clerkship in general practice: a survey of alumni 6 to 8 years after graduation
There is a worldwide recruitment and retention crisis in general practice. Workforce planning has identified the need to train more general practitioners as an urgent priority. Exposure of medical students to ...
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Patient Satisfaction in Emergency General Surgery: A Prospective Cross-Sectional Study
The importance of the patient experience is increasingly being recognised. However, there is a dearth of studies regarding factors affecting patient-reported outcomes in emergency general surgery (EGS), includ...
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Prognostic Differences in ISUP Grade Group 4: a Systematic Review and Meta-Analysis
The ISUP (Internal Society of Urologic Pathology) recently adopted a five-tiered prognostication system. There is evidence to suggest that the ISUP grade group 4 is a heterogeneous entity regarding prognosis. ...
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Open AccessDoes urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
Post-operative urinary incontinence is a significant concern for patients choosing to undergo a radical prostatectomy (RP) for treatment of prostate cancer. The aim of our study was to determine the effect of ...
