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Article
Open AccessInfluence of a chronic beta-blocker therapy on perioperative opioid consumption – a post hoc secondary analysis
Beta-blocker (BB) therapy plays a central role in the treatment of cardiovascular diseases. An increasing number of patients with cardiovascular diseases undergoe noncardiac surgery, where opioids are an integ...
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Article
Open AccessChronic Naltrexone Therapy Is Associated with Improved Cardiac Function in Volume Overloaded Rats
Myocardial opioid receptors were demonstrated in animals and humans and seem to colocalize with membranous and sarcolemmal calcium channels of the excitation–contraction coupling in the left ventricle (LV). Th...
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Article
Microvascular responses to (hyper-)gravitational stress by short-arm human centrifuge: arteriolar vasoconstriction and venous pooling
We hypothesized that lower body microvessels are particularly challenged during exposure to gravity and hypergravity leading to failure of resistance vessels to withstand excessive transmural pressure during h...
