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Article
Open AccessDesign of ANCHOR-RA: a multi-national cross-sectional study on screening for interstitial lung disease in patients with rheumatoid arthritis
Patients with rheumatoid arthritis (RA) are at risk of develo** interstitial lung disease (ILD), which is associated with high mortality. Screening tools based on risk factors are needed to decide which pati...
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Article
Open AccessDisease trajectories in interstitial lung diseases – data from the EXCITING-ILD registry
Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with different disease trajectories. Progression (PF-ILD) occurs in up to 50% of patients and is associated with ...
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Article
Open AccessmiR-Blood – a small RNA atlas of human blood components
miR-Blood is a high-quality, small RNA expression atlas for the major components of human peripheral blood (plasma, erythrocytes, thrombocytes, monocytes, neutrophils, eosinophils, basophils, natural killer cells...
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Article
Open AccessHospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry
Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with more than 200 entities and relevant differences in disease course and prognosis. Little data is available on...
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Article
Open AccessWeight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial
Lower body mass index (BMI) and weight loss have been associated with worse outcomes in some studies in patients with pulmonary fibrosis. We analyzed outcomes in subgroups by BMI at baseline and associations b...
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Article
Open AccessInvestigating significant health trends in progressive fibrosing interstitial lung disease (INSIGHTS-ILD): rationale, aims and design of a nationwide prospective registry
The progressive course of pulmonary fibrosis (PPF) is observed with variable prevalence in different entities of fibrosing interstitial lung disease (fILD). PPF is characterised by worsening respiratory sympto...
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Article
Open AccessStudy protocol of an international patient-led registry in patients with pulmonary fibrosis using online home monitoring: I-FILE
Pulmonary fibrosis (PF) is caused by a heterogeneous group of diseases, with a high inter-individual variability in disease trajectory. Identifying disease progression in patients with PF has impact on clinica...
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Article
„Enthusiast meets the Experienced“: Pneumo meets … Rheumatologie
Eine Vielzahl komplexer pulmonaler Krankheitsbilder erfordert eine enge Zusammenarbeit zwischen PneumologIn und RheumatologIn. So kann nahezu jede rheumatische Systemerkrankung mit einer interstitiellen Lungen...
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Living Reference Work Entry In depth
Medikamenteninduzierte interstitielle Lungenerkrankungen
Interstitielle Lungenerkrankungen (ILDs) umfassen eine heterogene Gruppe verschiedener Lungenerkrankungen, die das Interstitium und/oder die Alveolen betreffen. ILDs werden unterteilt in idiopathische Formen, ...
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Article
Open AccessAnti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial
Patients with cancer are at high risk of severe coronavirus disease 2019 (COVID-19), with high morbidity and mortality. Furthermore, impaired humoral response renders severe acute respiratory syndrome coronavi...
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Article
Open AccessThoracic surgery in the non-intubated spontaneously breathing patient
The interest in non-intubated video-assisted thoracic surgery (NIVATS) has risen over the last decade and numerous terms have been used to describe this technique. They all have in common, that the surgical pr...
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Article
Open AccessClusters of comorbidities in fibrotic hypersensitivity pneumonitis
Hypersensitivity pneumonitis (HP) is a type of interstitial lung disease (ILD) with a variable disease course and prognosis ranging from inflammatory and self-limiting to irreversible and progressive pulmonary...
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Article
Open AccessA review of the challenges, learnings and future directions of home handheld spirometry in interstitial lung disease
Patients with interstitial lung disease (ILD) require regular physician visits and referral to specialist ILD clinics. Difficulties or delays in accessing care can limit opportunities to monitor disease trajec...
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Article
Open AccessProtocol of the TREASURE study: Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease – a randomized, open-label, multicenter phase II trial
Recently, the combination of the programmed death-ligand 1 (PD-L1) inhibitor atezolizumab with first-line chemotherapy has demonstrated to improve outcome for patients with advanced small cell lung cancer (SCL...
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Article
Open AccessComparing outcomes of ILD patients managed in specialised versus non-specialised centres
Early appropriate diagnosis and treatment of interstitial lung diseases (ILD) is crucial to slow disease progression and improve survival. Yet it is unknown whether initial management in an expert centre is as...
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Article
Open AccessLong-term evaluation of the safety and efficacy of recombinant human pentraxin-2 (rhPTX-2) in patients with idiopathic pulmonary fibrosis (IPF): an open-label extension study
Recombinant human pentraxin-2 (rhPTX-2) significantly decreased decline in percent predicted forced vital capacity (FVC) and stabilized 6-min walk distance (6MWD) in patients with idiopathic pulmonary fibrosis...
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Article
Open AccessYouTube-videos for patient education in lymphangioleiomyomatosis?
The Internet is commonly used by patients to acquire health information. To date, no studies have evaluated the quality of information available on YouTube regarding lymphangioleiomyomatosis (LAM). Our aim was...
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Article
Open AccessEpidemiology, healthcare utilization, and related costs among patients with IPF: results from a German claims database analysis
Idiopathic pulmonary fibrosis (IPF) is a progressive form of fibrosing interstitial pneumonia with poor survival. This study provides insight into the epidemiology, cost, and disease course of IPF in Germany.
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Article
Open AccessComorbidities in unclassifiable interstitial lung disease
Comorbidities are common in interstitial lung diseases (ILD) and have an important association with survival, but the frequency and prognostic impact of comorbidities in unclassifiable interstitial lung diseas...
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Article
Entwicklung und Fortschritt bei interstitiellen Lungenerkrankungen
Im Bereich der interstitiellen Lungenerkrankungen (ILD) waren in den letzten Jahren sehr große Fortschritte in Diagnostik und Therapie zu verzeichnen. Hierzu zählt auch ein verbessertes Verständnis interstitie...