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Article
Self-organized intracellular twisters
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy and information flows is disrupted. Global coordination is no less important in single cell...
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Article
Laser ablation and fluid flows reveal the mechanism behind spindle and centrosome positioning
Few techniques are available for studying the nature of forces that drive subcellular dynamics. Here we develop two complementary ones. The first is femtosecond stereotactic laser ablation, which rapidly creat...
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Article
Open AccessHyperuniformity and phase enrichment in vortex and rotor assemblies
Ensembles of particles rotating in a two-dimensional fluid can exhibit chaotic dynamics yet develop signatures of hidden order. Such rotors are found in the natural world spanning vastly disparate length scale...
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Article
Motile dislocations knead odd crystals into whorls
The competition between thermal fluctuations and potential forces governs the stability of matter in equilibrium, in particular the proliferation and annihilation of topological defects. However, driving matte...
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Article
Open AccessTissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation
The phenomenon of tissue fluidity—cells’ ability to rearrange relative to each other in confluent tissues—has been linked to several morphogenetic processes and diseases, yet few molecular regulators of tissue...
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Article
Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors
In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular motors. In reconstituted cytos...
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Article
Self-straining of actively crosslinked microtubule networks
Cytoskeletal networks are foundational examples of active matter and central to self-organized structures in the cell. In vivo, these networks are active and densely crosslinked. Relating their large-scale dyn...
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Article
The odd free surface flows of a colloidal chiral fluid
In simple fluids, such as water, invariance under parity and time-reversal symmetry imposes that the rotation of constituent ‘atoms’ is determined by the flow and that viscous stresses damp motion. Activation ...
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Chapter
Theory of Active Suspensions
Active suspensions, of which a bath of swimming microorganisms is a paradigmatic example, denote large collections of individual particles or macromolecules capable of converting fuel into mechanical work and ...
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Article
Theoretical analysis of reverse-time correlation for idealized orientation tuning dynamics
A theoretical analysis is presented of a reverse-time correlation method used in experimentally investigating orientation tuning dynamics of neurons in the primary visual cortex. An exact mathematical characte...
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Chapter
Computing Microstructural Dynamics for Complex Fluids
Complex liquids such as polymeric or fiber suspensions are rich in interesting phenomena and as an area of scientific inquiry sits astride materials science and fluid dynamics. Materials science enters because...
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Article
Efficient and Accurate Time-Step** Schemes for Integrate-and-Fire Neuronal Networks
To avoid the numerical errors associated with resetting the potential following a spike in simulations of integrate-and-fire neuronal networks, Hansel et al. and Shelley independently developed a modified time...
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Chapter and Conference Paper
Spirals, Jets, and Pinches
It remains an open question in the mathematical and physical understanding of homogeneous, incompressible, three-dimensional fluids whether a singularity can form dynamically from smooth initial data. However,...
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Article
On the stability of time-harmonic localized states in a disordered nonlinear medium
We study the problem of localization in a disordered one-dimensional nonlinear medium modeled by the nonlinear Schrödinger equation. Devillard and Souillard have shown that almost every time-harmonic solution ...
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Chapter
Topological Transitions in Hele-Shaw Flow
The processes which lead to topological reconfiguration of fluid interfaces are studied in Hele-Shaw flow. This is motivated by recent experiments of droplet forma tion through the osculation of two interfaces...