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  1. No Access

    Article

    Self-organized intracellular twisters

    Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy and information flows is disrupted. Global coordination is no less important in single cell...

    Sayantan Dutta, Reza Farhadifar, Wen Lu, Gokberk Kabacaoğlu in Nature Physics (2024)

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    Article

    Laser ablation and fluid flows reveal the mechanism behind spindle and centrosome positioning

    Few techniques are available for studying the nature of forces that drive subcellular dynamics. Here we develop two complementary ones. The first is femtosecond stereotactic laser ablation, which rapidly creat...

    Hai-Yin Wu, Gökberk Kabacaoğlu, Ehssan Nazockdast, Huan-Cheng Chang in Nature Physics (2024)

  3. Article

    Open Access

    Hyperuniformity and phase enrichment in vortex and rotor assemblies

    Ensembles of particles rotating in a two-dimensional fluid can exhibit chaotic dynamics yet develop signatures of hidden order. Such rotors are found in the natural world spanning vastly disparate length scale...

    Naomi Oppenheimer, David B. Stein, Matan Yah Ben Zion in Nature Communications (2022)

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    Article

    Motile dislocations knead odd crystals into whorls

    The competition between thermal fluctuations and potential forces governs the stability of matter in equilibrium, in particular the proliferation and annihilation of topological defects. However, driving matte...

    Ephraim S. Bililign, Florencio Balboa Usabiaga, Yehuda A. Ganan in Nature Physics (2022)

  5. Article

    Open Access

    Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation

    The phenomenon of tissue fluidity—cells’ ability to rearrange relative to each other in confluent tissues—has been linked to several morphogenetic processes and diseases, yet few molecular regulators of tissue...

    Nabila Founounou, Reza Farhadifar, Giovanna M. Collu, Ursula Weber in Nature Communications (2021)

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    Article

    Comparison of explicit and mean-field models of cytoskeletal filaments with crosslinking motors

    In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular motors. In reconstituted cytos...

    Adam R. Lamson, Jeffrey M. Moore, Fang Fang in The European Physical Journal E (2021)

  7. No Access

    Article

    Self-straining of actively crosslinked microtubule networks

    Cytoskeletal networks are foundational examples of active matter and central to self-organized structures in the cell. In vivo, these networks are active and densely crosslinked. Relating their large-scale dyn...

    Sebastian Fürthauer, Bezia Lemma, Peter J. Foster in Nature Physics (2019)

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    Article

    The odd free surface flows of a colloidal chiral fluid

    In simple fluids, such as water, invariance under parity and time-reversal symmetry imposes that the rotation of constituent ‘atoms’ is determined by the flow and that viscous stresses damp motion. Activation ...

    Vishal Soni, Ephraim S. Bililign, Sofia Magkiriadou, Stefano Sacanna in Nature Physics (2019)

  9. No Access

    Chapter

    Theory of Active Suspensions

    Active suspensions, of which a bath of swimming microorganisms is a paradigmatic example, denote large collections of individual particles or macromolecules capable of converting fuel into mechanical work and ...

    David Saintillan, Michael J. Shelley in Complex Fluids in Biological Systems (2015)

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    Article

    Theoretical analysis of reverse-time correlation for idealized orientation tuning dynamics

    A theoretical analysis is presented of a reverse-time correlation method used in experimentally investigating orientation tuning dynamics of neurons in the primary visual cortex. An exact mathematical characte...

    Gregor Kovačič, Louis Tao, David Cai in Journal of Computational Neuroscience (2008)

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    Chapter

    Computing Microstructural Dynamics for Complex Fluids

    Complex liquids such as polymeric or fiber suspensions are rich in interesting phenomena and as an area of scientific inquiry sits astride materials science and fluid dynamics. Materials science enters because...

    Michael J. Shelley, Anna-Karin Tornberg in Handbook of Materials Modeling (2005)

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    Article

    Efficient and Accurate Time-Step** Schemes for Integrate-and-Fire Neuronal Networks

    To avoid the numerical errors associated with resetting the potential following a spike in simulations of integrate-and-fire neuronal networks, Hansel et al. and Shelley independently developed a modified time...

    Michael J. Shelley, Louis Tao in Journal of Computational Neuroscience (2001)

  13. No Access

    Chapter and Conference Paper

    Spirals, Jets, and Pinches

    It remains an open question in the mathematical and physical understanding of homogeneous, incompressible, three-dimensional fluids whether a singularity can form dynamically from smooth initial data. However,...

    Michael J. Shelley in IUTAM Symposium on Non-linear Singularities in Deformation and Flow (1999)

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    Article

    On the stability of time-harmonic localized states in a disordered nonlinear medium

    We study the problem of localization in a disordered one-dimensional nonlinear medium modeled by the nonlinear Schrödinger equation. Devillard and Souillard have shown that almost every time-harmonic solution ...

    Jared C. Bronski, David W. McLaughlin, Michael J. Shelley in Journal of Statistical Physics (1997)

  15. No Access

    Chapter

    Topological Transitions in Hele-Shaw Flow

    The processes which lead to topological reconfiguration of fluid interfaces are studied in Hele-Shaw flow. This is motivated by recent experiments of droplet forma tion through the osculation of two interfaces...

    Michael J. Shelley, Raymond E. Goldstein in Singularities in Fluids, Plasmas and Optics (1993)