-
Article
Open AccessAuthor Correction: Sustainability benefits of transitioning from current diets to plant-based alternatives or whole-food diets in Sweden
-
Article
Open AccessSustainability benefits of transitioning from current diets to plant-based alternatives or whole-food diets in Sweden
Plant-based alternatives (PBAs) are increasingly becoming part of diets. Here, we investigate the environmental, nutritional, and economic implications of replacing animal-source foods (ASFs) with PBAs or whol...
-
Article
Open AccessA high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell types with specific spatial distribution patterns and structural and functional properties1–3. Here we report a comp...
-
Article
Open AccessFear extinction is regulated by the activity of long noncoding RNAs at the synapse
Long noncoding RNAs (lncRNAs) represent a multidimensional class of regulatory molecules that are involved in many aspects of brain function. Emerging evidence indicates that lncRNAs are localized to the synap...
-
Article
Open AccessLiquidity and uncertainty: digital adaptation of a complex intervention for people with severe mental illness during the COVID-19 lockdown
This paper explores the extent to which the implementation and evaluation of a collaborative care model of face-to-face service delivery for people with severe mental illness was viable during the first UK loc...
-
Article
A multi-institutional study of surgical resident entrustability across multiple phases of care
There are concerns about the measurement burden that may be associated with Entrustable Professional Activities (EPAs) as well as the potential susceptibility of these ratings to influence from factors such as...
-
Article
Open AccessVegans, vegetarians, fish-eaters and meat-eaters in the UK show discrepant environmental impacts
Modelled dietary scenarios often fail to reflect true dietary practice and do not account for variation in the environmental burden of food due to sourcing and production methods. Here we link dietary data fro...
-
Chapter
A Whole Earth Approach to Nature-Positive Food: Biodiversity and Agriculture
Agriculture is the largest single source of environmental degradation, responsible for over 30% of global greenhouse gas (GHG) emissions, 70% of freshwater use and 80% of land conversion: it is the single larg...
-
Article
Open AccessIntravenous Golimumab in Patients with Polyarticular Juvenile Idiopathic Arthritis and Juvenile Psoriatic Arthritis and Subcutaneous Ustekinumab in Patients with Juvenile Psoriatic Arthritis: Extrapolation of Data from Studies in Adults and Adjacent Pediatric Populations
To describe the extrapolation approaches used to support intravenous (IV) golimumab for polyarticular juvenile idiopathic arthritis (pJIA) and juvenile psoriatic arthritis (jPsA) and subcutaneous (SC) ustekinu...
-
Article
Open AccessUsefulness of Postnatal Echocardiograms in Patients with Omphaloceles Who Previously Had a Normal Fetal Echocardiogram
Neonates with omphaloceles routinely have a transthoracic echocardiogram (TTE) performed due to a high association with congenital heart defects (CHD). The utility of a TTE in these patients with a normal feta...
-
Article
Open AccessAuthor Correction: Low-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer
-
Article
Internet Gaming Disorder: Compensating as a Draenei in World of Warcraft
The diagnosis of Gaming Disorder (GD) has been recently proposed in the beta draft of the 11th revision of the International Classification of Diseases (ICD-11) by the World Health Organization (WHO). This fol...
-
Article
Proactive conservation to prevent habitat losses to agricultural expansion
The projected loss of millions of square kilometres of natural ecosystems to meet future demand for food, animal feed, fibre and bioenergy crops is likely to massively escalate threats to biodiversity. Reducin...
-
Article
Open AccessLow-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer
Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared ...
-
Article
Poverty and Food Insecurity Predict Mealtime Structure: Mediating Pathways of Parent Disciplinary Practices and Depressive Symptoms
Structured, well-organized mealtime routines can provide physical and mental health benefits for children. Poverty and food insecurity (FI) are risk factors for less effective mealtime routines. However, the s...
-
Article
Innovation can accelerate the transition towards a sustainable food system
Future technologies and systemic innovation are critical for the profound transformation the food system needs. These innovations range from food production, land use and emissions, all the way to improved die...
-
Article
Open AccessA comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma
Purpose: This study compares the detection sensitivity of two separate liquid biopsy sources, cell-free (cf) DNA/RNA and extracellular vesicle (EV)-associated DNA/RNA (EV-DNA/RNA), to identify circulating Huma...
-
Article
Open AccessExposure to Infliximab During Pregnancy: Post-Marketing Experience
Women of childbearing potential are often treated with monoclonal antibodies to control chronic and debilitating inflammatory diseases. Remicade® (innovator infliximab [IFX]) may cross the placenta after the firs...
-
Article
Open AccessMeasuring the Activity of Mental Health Services in England: Variation in Categorising Activity for Payment Purposes
In the context of international interest in reforming mental health payment systems, national policy in England has sought to move towards an episodic funding approach. Patients are categorised into care clust...
-
Article
A laboratory model for the Parker spiral and magnetized stellar winds
Many rotating stars have magnetic fields that interact with the winds they produce. The Sun is no exception. The interaction between the Sun’s magnetic field and the solar wind gives rise to the heliospheric m...
