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  1. No Access

    Article

    Renewable Standard Reference Material for the Detection of TP53 Mutations

    Background: Numerous DNA-based tests are currently in use or under development for the detection of mutations associated with disease. Most of the current methods use PCR amplification technologi...

    Catherine D. O’Connell, Lois A. Tully, Joseph M. Devaney… in Molecular Diagnosis (2003)

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    Protocol

    Purification Methods for Preparing Polymerase Chain Reaction Products for Capillary Electrophoresis Analysis

    The analysis of polymerase chain reaction (PCR) products by capillary electrophoresis (CE) is often compromised by the presence of a high concentration of salt. Typical PCR reactions contain 50 mM of KCl and 1.5 ...

    Joseph M. Devaney, Michael A. Marino in Capillary Electrophoresis of Nucleic Acids (2001)

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    Protocol

    Low-Stringency Single Specific Primer-Amplified DNA Analysis by Capillary Electrophoresis

    Polymerase chain reaction (PCR) amplification is a relatively fast, sensitive method for characterizing discrete segments of the human genome for identity testing. Most PCR-based ty** assays that discriminat...

    Michael A. Marino in Capillary Electrophoresis of Nucleic Acids (2001)