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Article
Open AccessThe role of SOD2 and NOS2 genes in the molecular aspect of bladder cancer pathophysiology
Bladder cancer (BC) is a severe health problem of the genitourinary system and is characterised by a high risk of recurrence. According to the recent GLOBOCAN report, bladder cancer accounts for 3% of diagnose...
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Article
Open AccessOxidative stress parameters as biomarkers of bladder cancer development and progression
The epidemiological studies confirm that the overproduction of free radical is an important factor of cancer induction as well as development, and loss of antioxidant systems efficiency is associated with an i...
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Article
Open AccessThe Effect of Chronic Mild Stress and Venlafaxine on the Expression and Methylation Levels of Genes Involved in the Tryptophan Catabolites Pathway in the Blood and Brain Structures of Rats
A growing body of evidence suggests that depression may be associated with impairment of the tryptophan catabolites (TRYCATs) pathway. The present study investigated the effects of the chronic administration o...
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Article
Open AccessFlow cytometric analysis reveals the high levels of platelet activation parameters in circulation of multiple sclerosis patients
The epidemiological studies confirm an increased risk of cardiovascular disease in multiple sclerosis, especially prothrombotic events directly associated with abnormal platelet activity. The aim of our study ...
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Article
The comparison of peroxynitrite action on bovine, porcine and human fibrinogens
Subjects of bovine and porcine flocks are sometimes susceptible to death before time of slaughter, and some of those deaths may be due to cardiovascular problems connected with stress. The role of oxidative st...
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Article
Anthocyanins from red cabbage extract — evidence of protective effects on blood platelets
Red cabbage belongs to cruciferous vegetables recognized as a rich source of anthocyanins. Anthocyanins have a wide range of therapeutic advantages without adverse effects, including cardiovascular protective ...
