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176 Result(s)
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Article
Data-driven shortened Insomnia Severity Index (ISI): a machine learning approach
The Insomnia Severity Index (ISI) is a widely used questionnaire with seven items for identifying the risk of insomnia disorder. Although the ISI is still short, more shortened versions are emerging for repeat...
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Article
Open AccessPrior pneumococcal vaccination improves in-hospital mortality among elderly population hospitalized due to community-acquired pneumonia
Pneumococcal vaccination is a preventive method to reduce pneumonia related mortality. However, real-world data on efficacy of the pneumococcal vaccine in reducing mortality is lacking, especially in elderly p...
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Article
Open AccessBritish societies guideline on the management of emergencies in implantable left ventricular assist device recipients in transplant centres
An implantable left ventricular assist device (LVAD) is indicated as a bridge to transplantation or recovery in the United Kingdom (UK). The mechanism of action of the LVAD results in a unique state of haemody...
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A randomized comparison of three intubation techniques/tube materials for nasotracheal intubation
We sought to compare three intubation methods using different intubation techniques/tube materials for tube advancement from the nasal cavity into the oral cavity during nasotracheal intubation.
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Article
Open AccessRespiratory fit test panel representing population of Malaysia
The existing respiratory fit test panels (RFTPs) are based on Bivariate and Principal Component Analysis (PCA) which utilise American and Chinese head and facial dimensions. As RFTPs based on local facial anth...
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Open AccessPrognosis of mechanically ventilated patients with COVID-19 after failure of high-flow nasal cannula: a retrospective cohort study
There is an argument whether the delayed intubation aggravate the respiratory failure in Acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). We aimed to investigate th...
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Article
Relationship between airflow limitation in response to upper airway negative pressure during wakefulness and obstructive sleep apnea severity
The objective was to determine if alteration in airflow induced by negative pressure (NP) applied to participants’ upper airways during wakefulness, is related to obstructive sleep apnea (OSA) severity as dete...
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Article
Open AccessCorrection: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
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Article
Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomized controlled trials and propensity score-matched studies
Cardiogenic shock is associated with high mortality. In refractory shock, it is unclear if mechanical circulatory support (MCS) devices improve survival. We conducted a network meta-analysis to determine which...
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Open AccessUnderstanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
Bacterial colonization is an essential aspect of bronchiectasis. Although Haemophilus influenzae is a frequent colonizer in some regions, its clinical impacts are poorly understood. This study aimed to elucidate ...
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Article
Open AccessThe increasing burden of asthma acute care in Singapore: an update on 15-year population-level evidence
In Singapore, there is currently scarce population-based research informing the recent trends of asthma-related healthcare burdens. In this study, we investigated the past 25-year trends of asthma-related hosp...
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Open AccessComparative Treatment Persistence and Adherence to Endothelin Receptor Antagonists Among Patients with Pulmonary Arterial Hypertension in Japan: A Real-World Administrative Claims Database Study
Real-world data on the comparative effectiveness of endothelin receptor antagonists (ERAs; macitentan, bosentan, ambrisentan) for pulmonary arterial hypertension (PAH), particularly in Asian countries, are sca...
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Article
Open AccessDevelopment of obstetric anesthesia core competencies for USA residency programs through a Delphi process
The standard for anesthesia residency training in the USA mainly relies on the Accreditation Council for Graduate Medical Education (ACGME) Outcome Project, a framework that lacks specific directives for subsp...
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Open AccessMachine diagnosis of chronic obstructive pulmonary disease using a novel fast-response capnometer
Although currently most widely used in mechanical ventilation and cardiopulmonary resuscitation, features of the carbon dioxide (CO2) waveform produced through capnometry have been shown to correlate with V/Q mis...
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Open AccessIntegrin α10β1-selected mesenchymal stem cells reduced hypercoagulopathy in a porcine model of acute respiratory distress syndrome
Mesenchymal stem cells (MSCs) have been studied for their potential benefits in treating acute respiratory distress syndrome (ARDS) and have reported mild effects when trialed within human clinical trials. MSC...
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High-Resolution EEG Characterization of Sleep Neurophysiology
The continuing advances in the technology of electroencephalography (EEG) in sleep are providing new insights into the neurophysiological mechanisms of sleep that are relevant to both health and disease. Sleep...
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Article
Open AccessAnti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the phase 2 PANAMO trial
We recently reported in the phase 3 PANAMO trial that selectively blocking complement 5a (C5a) with vilobelimab led to improved survival in critically ill COVID-19 patients. C5a is an important contributor to ...
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Open AccessAssociation of Underlying Comorbidities and Sites of tuberculosis: an analysis using surveillance data
Tuberculosis (TB) is a highly heterogeneous disease that can affect any organ. Extrapulmonary TB (EPTB) is more difficult to diagnose due to various clinical presentations. Depending on the characteristics of ...
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Article
Ultrasound assessment of gastric volume in older adults after drinking carbohydrate-containing fluids: a prospective, nonrandomized, and noninferiority comparative study
The aim of this study was to evaluate the safety of drinking carbohydrate-containing fluids two hours prior to surgery in older adults using ultrasonography.
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Article
Open AccessEvaluation of the synergistic impact of needle and forceps biopsy with electromagnetic navigation bronchoscopy: the CONFIDENT-ENB trial design
Electromagnetic navigation bronchoscopy (ENB) is an emerging advanced imaging-guided bronchoscopy technique for diagnosing peripheral lung lesions. However, the selection strategy for the optimal biopsy device...