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  1. Article

    Open Access

    Characteristics of infections with ancestral, Beta and Delta variants of SARS-CoV-2 in the PHIRST-C community cohort study, South Africa, 2020-2021

    Data on the characteristics of individuals with mild and asymptomatic infections with different SARS-CoV-2 variants are limited. We therefore compared the characteristics of individuals infected with ancestral...

    Cheryl Cohen, Jackie Kleynhans, Anne von Gottberg in BMC Infectious Diseases (2024)

  2. Article

    Open Access

    Incidence and transmission of respiratory syncytial virus in urban and rural South Africa, 2017-2018

    Data on respiratory syncytial virus (RSV) incidence and household transmission are limited. To describe RSV incidence and transmission, we conducted a prospective cohort study in rural and urban communities in...

    Cheryl Cohen, Jackie Kleynhans, Jocelyn Moyes in Nature Communications (2024)

  3. Article

    Open Access

    The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016

    Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies. We estimated the cost of RSV-associated illness in...

    Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow in BMC Medicine (2023)

  4. Article

    Open Access

    The burden of RSV-associated illness in children aged < 5 years, South Africa, 2011 to 2016

    Vaccines and monoclonal antibodies to protect the very young infant against the respiratory syncytial virus (RSV)-associated illness are effective for limited time periods. We aimed to estimate age-specific bu...

    Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow in BMC Medicine (2023)

  5. Article

    Open Access

    Rapidly shifting immunologic landscape and severity of SARS-CoV-2 in the Omicron era in South Africa

    South Africa was among the first countries to detect the SARS-CoV-2 Omicron variant. However, the size of its Omicron BA.1 and BA.2 subvariants (BA.1/2) wave remains poorly understood. We analyzed sequential s...

    Kaiyuan Sun, Stefano Tempia, Jackie Kleynhans, Anne von Gottberg in Nature Communications (2023)

  6. Article

    Open Access

    A cross-sectional study measuring contact patterns using diaries in an urban and a rural community in South Africa, 2018

    Describing contact patterns is crucial to understanding infectious disease transmission dynamics and guiding targeted transmission mitigation interventions. Data on contact patterns in Africa, especially South...

    Jackie Kleynhans, Stefano Tempia, Meredith L. McMorrow in BMC Public Health (2021)

  7. Article

    Open Access

    Responses to hypothetical health scenarios overestimate healthcare utilization for common infectious syndromes: a cross-sectional survey, South Africa, 2012

    Asking people how they would seek healthcare in a hypothetical situation can be an efficient way to estimate healthcare utilization, but it is unclear how intended healthcare use corresponds to actual healthca...

    Karen K. Wong, Adam L. Cohen, Neil A. Martinson, Shane A. Norris in BMC Infectious Diseases (2018)

  8. Article

    Open Access

    Incidence of medically attended influenza among residents of Shai-Osudoku and Ningo-Prampram Districts, Ghana, May 2013 – April 2015

    Influenza vaccination is recommended by the World Health Organization for high risk groups, yet few data exist on influenza disease burden in West Africa.

    Michael Preko Ntiri, Jazmin Duque, Meredith L. McMorrow in BMC Infectious Diseases (2016)

  9. Article

    Open Access

    Quality assurance of malaria rapid diagnostic tests used for routine patient care in rural Tanzania: microscopy versus real-time polymerase chain reaction

    The World Health Organization (WHO) recommends parasitologic confirmation of suspected malaria cases before treatment. Due to the limited availability of quality microscopy services, this recommendation has be...

    Irene M Masanja, Meredith L McMorrow, Mussa B Maganga, Debora Sumari in Malaria Journal (2015)

  10. Article

    Open Access

    Influenza vaccines and influenza antiviral drugs in Africa: are they available and do guidelines for their use exist?

    Influenza viruses cause significant morbidity and mortality in Africa, particularly among high-risk groups, but influenza vaccines and antiviral drugs may not be commonly available and used. The main aim of th...

    Jazmin Duque, Meredith L McMorrow, Adam L Cohen in BMC Public Health (2014)

  11. Article

    Open Access

    Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali

    Because of the emergence of chloroquine resistance in Mali, artemether-lumefantrine (AL) or artesunate-amodiaquine (AS+AQ) are recommended as first-line therapy for uncomplicated malaria, but have not been ava...

    Kassoum Kayentao, Hamma Maiga, Robert D Newman, Meredith L McMorrow in Malaria Journal (2009)

  12. No Access

    Article

    Diagnosis of Malaria

    Malaria is a leading cause of morbidity and mortality worldwide. Prompt diagnosis and treatment are critical factors in reducing morbidity and mortality, as delayed treatment of malaria increases the risk of d...

    Dr Rachel N. Bronzan, Meredith L. McMorrow in Molecular Diagnosis & Therapy (2008)