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  1. No Access

    Article

    T790M mutation upconversion fluorescence biosensor via mild ATRP strategy and site-specific DNA cleavage of restriction endonuclease

    A unique combination of a specific nucleic acid restriction endonuclease (REase) and atom transfer radical polymerization (ATRP) signal amplification strategy was employed for the detection of T790M mutations ...

    Yanju Liu, Liang Guo, Mengyuan Hou, Haiyang Gao, Yuanmeng Ke… in Microchimica Acta (2024)

  2. Article

    Open Access

    Construction of boron-stereogenic compounds via enantioselective Cu-catalyzed desymmetric B–H bond insertion reaction

    Compared with the well-developed carbon-stereogenic chemistry, the construction of boron-stereogenic compounds remains undeveloped and challenging. Herein, the previously elusive catalytic enantioselective con...

    Guan Zhang, Zhihan Zhang, Mengyuan Hou, ** Cai, Kai Yang… in Nature Communications (2022)

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  3. No Access

    Article

    Efficacy of triptans for the treatment of acute migraines: a quantitative comparison based on the dose-effect and time-course characteristics

    This study aimed to establish a pharmacodynamic model to quantitatively compare the efficacy characteristics of seven kinds of triptans and their different dosage forms in the treatment of acute migraines.

    Mengyuan Hou, Hongxia Liu, Yunfei Li, Ling Xu… in European Journal of Clinical Pharmacology (2019)